Self-propagating, protease-resistant, recombinant prion protein conformers with or without in vivo pathogenicity

• Fei Wang,

  Roles Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliation Center for Neurodegenerative Science, Van Andel Research Institute, Grand Rapids, Michigan, United States of America

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• Xinhe Wang,

  Roles Investigation, Visualization, Writing – review & editing

  Affiliation Center for Neurodegenerative Science, Van Andel Research Institute, Grand Rapids, Michigan, United States of America

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• Christina D. Orrú,

  Roles Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – review & editing

  Affiliation Rocky Mountain Laboratories, National Institute of Allergy & Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America

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• Bradley R. Groveman,

  Roles Investigation, Visualization, Writing – review & editing

  Affiliation Rocky Mountain Laboratories, National Institute of Allergy & Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America

  http://orcid.org/0000-0002-5059-7672

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• Krystyna Surewicz,

  Roles Funding acquisition, Investigation, Methodology, Supervision, Validation, Visualization, Writing – review & editing

  Affiliation Department of Physiology and Biophysics, Case Western Reserve University, Cleveland, Ohio, United States of America

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• Romany Abskharon,

  Roles Investigation, Visualization, Writing – review & editing

  Affiliations Center for Neurodegenerative Science, Van Andel Research Institute, Grand Rapids, Michigan, United States of America, National Institute of Oceanography and Fisheries (NIOF), Cairo, Egypt

  http://orcid.org/0000-0003-1350-0189

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• Morikazu Imamura,

  Roles Resources, Writing – review & editing

  Current address: Department of Infectious Diseases, Faculty of Medicine, University of Miyazaki, Kiyotake, Miyazaki, JAPAN

  Affiliation National Institute of Animal Health, National Agriculture and Food Research Organization (NARO), Tsukuba, Ibaraki, Japan

  http://orcid.org/0000-0002-7010-6228

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• Takashi Yokoyama,

  Roles Resources

  Affiliation National Institute of Animal Health, National Agriculture and Food Research Organization (NARO), Tsukuba, Ibaraki, Japan

  http://orcid.org/0000-0002-5422-542X

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• Yong-Sun Kim,

  Roles Resources, Writing – review & editing

  Affiliation Ilsong Institute of Life Science, Korea CJD Diagnostic Center, Hallym University, Anyang, Republic of Korea

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• Kayla J. Vander Stel,

  Roles Investigation, Visualization

  Affiliation Center for Neurodegenerative Science, Van Andel Research Institute, Grand Rapids, Michigan, United States of America

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• Kumar Sinniah,

  Roles Investigation, Visualization, Writing – review & editing

  Affiliation Department of Chemistry and Biochemistry, Calvin College, Grand Rapids, Michigan, United States of America

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• Suzette A. Priola,

  Roles Funding acquisition, Resources, Writing – review & editing

  Affiliation Rocky Mountain Laboratories, National Institute of Allergy & Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America

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• Witold K. Surewicz,

  Roles Funding acquisition, Methodology, Supervision, Validation, Writing – review & editing

  Affiliation Department of Physiology and Biophysics, Case Western Reserve University, Cleveland, Ohio, United States of America

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• Byron Caughey,

  Roles Funding acquisition, Methodology, Supervision, Validation, Writing – review & editing

  Affiliation Rocky Mountain Laboratories, National Institute of Allergy & Infectious Diseases, National Institutes of Health, Hamilton, Montana, United States of America

  http://orcid.org/0000-0002-3928-6101

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• Jiyan Ma

  Roles Conceptualization, Data curation, Funding acquisition, Methodology, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: Jiyan.Ma@vai.org

  Affiliation Center for Neurodegenerative Science, Van Andel Research Institute, Grand Rapids, Michigan, United States of America

  http://orcid.org/0000-0001-7150-1898

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