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Open Access
Peer-reviewed
Research Article
Helicobacter pylori gene silencing in vivo demonstrates urease is essential for chronic infection
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Aleksandra W. Debowski ,
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Validation, Visualization, Writing – original draft, Writing – review & editing
* E-mail: aleksandra.debowski@uwa.edu.au
Affiliations Helicobacter pylori Research Laboratory, Marshall Centre for Infectious Disease Research and Training, School of Biomedical Sciences, University of Western Australia, Nedlands, Western Australia, Australia, Ondek Pty. Ltd., Marshall Centre for Infectious Disease Research and Training, School of Biomedical Sciences, University of Western Australia, Nedlands, Western Australia, Australia, School of Molecular Sciences, University of Western Australia, Crawley, Western Australia, Australia
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Senta M. Walton,
Roles Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Validation, Visualization, Writing – review & editing
Affiliations Helicobacter pylori Research Laboratory, Marshall Centre for Infectious Disease Research and Training, School of Biomedical Sciences, University of Western Australia, Nedlands, Western Australia, Australia, Ondek Pty. Ltd., Marshall Centre for Infectious Disease Research and Training, School of Biomedical Sciences, University of Western Australia, Nedlands, Western Australia, Australia
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Eng-Guan Chua,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliation Helicobacter pylori Research Laboratory, Marshall Centre for Infectious Disease Research and Training, School of Biomedical Sciences, University of Western Australia, Nedlands, Western Australia, Australia
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Alfred Chin-Yen Tay,
Roles Data curation, Formal analysis, Project administration, Resources
Affiliation Helicobacter pylori Research Laboratory, Marshall Centre for Infectious Disease Research and Training, School of Biomedical Sciences, University of Western Australia, Nedlands, Western Australia, Australia
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Tingting Liao,
Roles Investigation
Affiliations Helicobacter pylori Research Laboratory, Marshall Centre for Infectious Disease Research and Training, School of Biomedical Sciences, University of Western Australia, Nedlands, Western Australia, Australia, Ondek Pty. Ltd., Marshall Centre for Infectious Disease Research and Training, School of Biomedical Sciences, University of Western Australia, Nedlands, Western Australia, Australia
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Binit Lamichhane,
Roles Formal analysis, Investigation
Affiliation Helicobacter pylori Research Laboratory, Marshall Centre for Infectious Disease Research and Training, School of Biomedical Sciences, University of Western Australia, Nedlands, Western Australia, Australia
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Robyn Himbeck,
Roles Investigation, Methodology
Affiliation Ondek Pty. Ltd., Marshall Centre for Infectious Disease Research and Training, School of Biomedical Sciences, University of Western Australia, Nedlands, Western Australia, Australia
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Keith A. Stubbs,
Roles Funding acquisition, Resources, Supervision, Validation, Visualization, Writing – review & editing
Affiliation School of Molecular Sciences, University of Western Australia, Crawley, Western Australia, Australia
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Barry J. Marshall,
Roles Conceptualization, Funding acquisition
Affiliations Helicobacter pylori Research Laboratory, Marshall Centre for Infectious Disease Research and Training, School of Biomedical Sciences, University of Western Australia, Nedlands, Western Australia, Australia, Ondek Pty. Ltd., Marshall Centre for Infectious Disease Research and Training, School of Biomedical Sciences, University of Western Australia, Nedlands, Western Australia, Australia
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Alma Fulurija,
Roles Project administration
Affiliations Helicobacter pylori Research Laboratory, Marshall Centre for Infectious Disease Research and Training, School of Biomedical Sciences, University of Western Australia, Nedlands, Western Australia, Australia, Ondek Pty. Ltd., Marshall Centre for Infectious Disease Research and Training, School of Biomedical Sciences, University of Western Australia, Nedlands, Western Australia, Australia
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Mohammed Benghezal
Roles Conceptualization, Project administration, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing
Current address: Swiss Vitamin Institute, Epalinges, Switzerland
Affiliations Helicobacter pylori Research Laboratory, Marshall Centre for Infectious Disease Research and Training, School of Biomedical Sciences, University of Western Australia, Nedlands, Western Australia, Australia, Ondek Pty. Ltd., Marshall Centre for Infectious Disease Research and Training, School of Biomedical Sciences, University of Western Australia, Nedlands, Western Australia, Australia
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Helicobacter pylori gene silencing in vivo demonstrates urease is essential for chronic infection
- Aleksandra W. Debowski,
- Senta M. Walton,
- Eng-Guan Chua,
- Alfred Chin-Yen Tay,
- Tingting Liao,
- Binit Lamichhane,
- Robyn Himbeck,
- Keith A. Stubbs,
- Barry J. Marshall,
- Alma Fulurija
![PLOS](/resource/img/logo-plos.png)
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- Published: June 23, 2017
- https://doi.org/10.1371/journal.ppat.1006464