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Open Access
Peer-reviewed
Research Article
Digoxin reveals a functional connection between HIV-1 integration preference and T-cell activation
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Alexander Zhyvoloup ,
Contributed equally to this work with: Alexander Zhyvoloup, Anat Melamed
Roles Formal analysis, Investigation, Validation, Visualization
Affiliation Division of Infection & Immunity, University College London, London, United Kingdom
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Anat Melamed ,
Contributed equally to this work with: Alexander Zhyvoloup, Anat Melamed
Roles Data curation, Formal analysis, Investigation, Methodology, Software, Writing – review & editing
Affiliation Department of Medicine, Imperial College, St. Mary's Campus, London, United Kingdom
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Ian Anderson,
Roles Investigation, Methodology
Affiliation Division of Infection & Immunity, University College London, London, United Kingdom
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Delphine Planas,
Roles Investigation, Validation, Visualization
Affiliation Department of Microbiology, Infectiology and Immunology, Faculty of Medicine, University of Montreal and the Research Centre of the CHUM, Montreal, Québec, Canada
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Chen-Hsuin Lee,
Roles Investigation
Affiliation Division of Infection & Immunity, University College London, London, United Kingdom
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Janos Kriston-Vizi,
Roles Data curation, Formal analysis, Funding acquisition
Affiliation MRC Laboratory for Molecular Cell Biology, University College London, London, United Kingdom
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Robin Ketteler,
Roles Funding acquisition
Affiliation MRC Laboratory for Molecular Cell Biology, University College London, London, United Kingdom
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Andy Merritt,
Roles Resources
Affiliation Centre for Therapeutics Discovery, MRC Technology, Mill Hill, London, United Kingdom
⨯ - Jean-Pierre Routy,
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Petronela Ancuta,
Roles Funding acquisition, Project administration, Supervision, Visualization, Writing – review & editing
Affiliation Department of Microbiology, Infectiology and Immunology, Faculty of Medicine, University of Montreal and the Research Centre of the CHUM, Montreal, Québec, Canada
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Charles R. M. Bangham,
Roles Funding acquisition, Project administration, Supervision, Writing – review & editing
Affiliation Department of Medicine, Imperial College, St. Mary's Campus, London, United Kingdom
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Ariberto Fassati
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Project administration, Supervision, Visualization, Writing – original draft
* E-mail: a.fassati@ucl.ac.uk
Affiliation Division of Infection & Immunity, University College London, London, United Kingdom
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Digoxin reveals a functional connection between HIV-1 integration preference and T-cell activation
- Alexander Zhyvoloup,
- Anat Melamed,
- Ian Anderson,
- Delphine Planas,
- Chen-Hsuin Lee,
- Janos Kriston-Vizi,
- Robin Ketteler,
- Andy Merritt,
- Jean-Pierre Routy,
- Petronela Ancuta
- Published: July 20, 2017
- https://doi.org/10.1371/journal.ppat.1006460