Promiscuous signaling by a regulatory system unique to the pandemic PMEN1 pneumococcal lineage

Anagha Kadam; Rory A. Eutsey; Jason Rosch; Xinyu Miao; Mark Longwell; Wenjie Xu; Carol A. Woolford; Todd Hillman; Anfal Shakir Motib; Hasan Yesilkaya; Aaron P. Mitchell; N. Luisa Hiller

doi:10.1371/journal.ppat.1006339

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Open Access

Peer-reviewed

Research Article

Promiscuous signaling by a regulatory system unique to the pandemic PMEN1 pneumococcal lineage

Anagha Kadam,

Affiliation Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America

http://orcid.org/0000-0003-2216-3065

⨯
Rory A. Eutsey,

Affiliation Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America
⨯
Jason Rosch,

Affiliation Infectious Diseases, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
⨯
Xinyu Miao,

Affiliation Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America

http://orcid.org/0000-0003-0168-2288

⨯
Mark Longwell,

Affiliation Center of Excellence in Biofilm Research, Allegheny Health Network, Pittsburgh, Pennsylvania, United States of America
⨯
Wenjie Xu,

Affiliation Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America
⨯
Carol A. Woolford,

Affiliation Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America

http://orcid.org/0000-0001-6261-3468

⨯
Todd Hillman,

Affiliation Pittsburgh Ear Associates, Allegheny General Hospital, Pittsburgh, Pennsylvania, United States of America
⨯
Anfal Shakir Motib,

Affiliation Department of Infection, Immunity & Inflammation, University of Leicester, Leicester, United Kingdom
⨯
Hasan Yesilkaya,

Affiliation Department of Infection, Immunity & Inflammation, University of Leicester, Leicester, United Kingdom
⨯
Aaron P. Mitchell,

Affiliation Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America
⨯
N. Luisa Hiller

* E-mail: lhiller@andrew.cmu.edu

Affiliations Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, Pennsylvania, United States of America, Center of Excellence in Biofilm Research, Allegheny Health Network, Pittsburgh, Pennsylvania, United States of America

http://orcid.org/0000-0001-6572-1368

⨯

Promiscuous signaling by a regulatory system unique to the pandemic PMEN1 pneumococcal lineage

Anagha Kadam,
Rory A. Eutsey,
Jason Rosch,
Xinyu Miao,
Mark Longwell,
Wenjie Xu,
Carol A. Woolford,
Todd Hillman,
Anfal Shakir Motib,
Hasan Yesilkaya

Published: May 18, 2017
https://doi.org/10.1371/journal.ppat.1006339

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