Kaposi Sarcoma Herpesvirus (KSHV) Latency-Associated Nuclear Antigen (LANA) recruits components of the MRN (Mre11-Rad50-NBS1) repair complex to modulate an innate immune signaling pathway and viral latency

Giuseppe Mariggiò; Sandra Koch; Guigen Zhang; Magdalena Weidner-Glunde; Jessica Rückert; Semra Kati; Susann Santag; Thomas F. Schulz

doi:10.1371/journal.ppat.1006335

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Peer-reviewed

Research Article

Kaposi Sarcoma Herpesvirus (KSHV) Latency-Associated Nuclear Antigen (LANA) recruits components of the MRN (Mre11-Rad50-NBS1) repair complex to modulate an innate immune signaling pathway and viral latency

Giuseppe Mariggiò,

Affiliations Institute of Virology, Hannover Medical School, Hannover, Germany, German Centre for Infection Research, Hannover-Braunschweig Site, Germany
⨯
Sandra Koch,

Affiliations Institute of Virology, Hannover Medical School, Hannover, Germany, German Centre for Infection Research, Hannover-Braunschweig Site, Germany

http://orcid.org/0000-0003-3759-9996

⨯
Guigen Zhang,

Affiliations Institute of Virology, Hannover Medical School, Hannover, Germany, German Centre for Infection Research, Hannover-Braunschweig Site, Germany
⨯
Magdalena Weidner-Glunde,

Affiliations Institute of Virology, Hannover Medical School, Hannover, Germany, German Centre for Infection Research, Hannover-Braunschweig Site, Germany
⨯
Jessica Rückert,

Affiliations Institute of Virology, Hannover Medical School, Hannover, Germany, German Centre for Infection Research, Hannover-Braunschweig Site, Germany
⨯
Semra Kati,

Affiliations Institute of Virology, Hannover Medical School, Hannover, Germany, German Centre for Infection Research, Hannover-Braunschweig Site, Germany

http://orcid.org/0000-0003-4606-8441

⨯
Susann Santag,

Affiliations Institute of Virology, Hannover Medical School, Hannover, Germany, German Centre for Infection Research, Hannover-Braunschweig Site, Germany
⨯
Thomas F. Schulz

* E-mail: schulz.thomas@mh-hannover.de

Affiliations Institute of Virology, Hannover Medical School, Hannover, Germany, German Centre for Infection Research, Hannover-Braunschweig Site, Germany

http://orcid.org/0000-0001-8792-5345

⨯

Kaposi Sarcoma Herpesvirus (KSHV) Latency-Associated Nuclear Antigen (LANA) recruits components of the MRN (Mre11-Rad50-NBS1) repair complex to modulate an innate immune signaling pathway and viral latency

Giuseppe Mariggiò,
Sandra Koch,
Guigen Zhang,
Magdalena Weidner-Glunde,
Jessica Rückert,
Semra Kati,
Susann Santag,
Thomas F. Schulz

Published: April 21, 2017
https://doi.org/10.1371/journal.ppat.1006335

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