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Open Access
Peer-reviewed
Research Article
A novel Zika virus mouse model reveals strain specific differences in virus pathogenesis and host inflammatory immune responses
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Shashank Tripathi,
Affiliations Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Vinod R. M. T. Balasubramaniam,
Affiliations Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Julia A. Brown,
Affiliations Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, The Graduate School of Biological Sciences at the Icahn School of Medicine at Mount Sinai, Microbiology Training Area, New York, New York, United States of America
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Ignacio Mena,
Affiliation Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Alesha Grant,
Affiliations Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, The Graduate School of Biological Sciences at the Icahn School of Medicine at Mount Sinai, Microbiology Training Area, New York, New York, United States of America
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Susana V. Bardina,
Affiliations Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, The Graduate School of Biological Sciences at the Icahn School of Medicine at Mount Sinai, Microbiology Training Area, New York, New York, United States of America
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Kevin Maringer,
Current address: University of Surrey, Surrey, United Kingdom
Affiliation Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Megan C. Schwarz,
Affiliation Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Ana M. Maestre,
Affiliation Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Marion Sourisseau,
Affiliation Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Randy A. Albrecht,
Affiliations Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Florian Krammer,
Affiliation Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Matthew J. Evans,
Affiliation Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Ana Fernandez-Sesma,
Affiliation Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Jean K. Lim,
Affiliation Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Adolfo García-Sastre
* E-mail: adolfo.garcia-sastre@mssm.edu
Affiliations Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, Global Health and Emerging Pathogens Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America, Department of Medicine, Division of Infectious Diseases, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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A novel Zika virus mouse model reveals strain specific differences in virus pathogenesis and host inflammatory immune responses
- Shashank Tripathi,
- Vinod R. M. T. Balasubramaniam,
- Julia A. Brown,
- Ignacio Mena,
- Alesha Grant,
- Susana V. Bardina,
- Kevin Maringer,
- Megan C. Schwarz,
- Ana M. Maestre,
- Marion Sourisseau
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- Published: March 9, 2017
- https://doi.org/10.1371/journal.ppat.1006258