Delineating CD4 dependency of HIV-1: Adaptation to infect low level CD4 expressing target cells widens cellular tropism but severely impacts on envelope functionality

• David Beauparlant,

  Affiliation Institute of Medical Virology, University of Zurich, Zurich, Switzerland

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• Peter Rusert,

  Affiliation Institute of Medical Virology, University of Zurich, Zurich, Switzerland

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• Carsten Magnus,

  Current address: Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland

  Affiliation Institute of Medical Virology, University of Zurich, Zurich, Switzerland

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• Claus Kadelka,

  Affiliations Institute of Medical Virology, University of Zurich, Zurich, Switzerland, Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland

  http://orcid.org/0000-0002-5712-8529

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• Jacqueline Weber,

  Affiliation Institute of Medical Virology, University of Zurich, Zurich, Switzerland

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• Therese Uhr,

  Affiliation Institute of Medical Virology, University of Zurich, Zurich, Switzerland

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• Osvaldo Zagordi,

  Affiliation Institute of Medical Virology, University of Zurich, Zurich, Switzerland

  http://orcid.org/0000-0002-9082-8607

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• Corinna Oberle,

  Current address: Gilead Sciences Switzerland Sarl, Zug, Switzerland

  Affiliation Institute of Medical Virology, University of Zurich, Zurich, Switzerland

  http://orcid.org/0000-0001-5784-6048

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• Maria J. Duenas-Decamp,

  Affiliation Program in Molecular Medicine, Biotech II, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

  http://orcid.org/0000-0003-2020-6471

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• Paul R. Clapham,

  Affiliation Program in Molecular Medicine, Biotech II, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

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• Karin J. Metzner,

  Affiliations Institute of Medical Virology, University of Zurich, Zurich, Switzerland, Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland

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• Huldrych F. Günthard,

  Affiliations Institute of Medical Virology, University of Zurich, Zurich, Switzerland, Division of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland

  http://orcid.org/0000-0002-1142-6723

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• Alexandra Trkola

  * E-mail: trkola.alexandra@virology.uzh.ch

  Affiliation Institute of Medical Virology, University of Zurich, Zurich, Switzerland

  http://orcid.org/0000-0003-1013-876X

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