Hepatic deficiency of the pioneer transcription factor FoxA restricts hepatitis B virus biosynthesis by the developmental regulation of viral DNA methylation

Vanessa C. McFadden; Rasha E. Shalaby; Saira Iram; Claudia E. Oropeza; Jennifer A. Landolfi; Alexander V. Lyubimov; Mark Maienschein-Cline; Stefan J. Green; Klaus H. Kaestner; Alan McLachlan

doi:10.1371/journal.ppat.1006239

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Open Access

Peer-reviewed

Research Article

Hepatic deficiency of the pioneer transcription factor FoxA restricts hepatitis B virus biosynthesis by the developmental regulation of viral DNA methylation

Vanessa C. McFadden,

Affiliation Department of Microbiology and Immunology College of Medicine University of Illinois at Chicago 909 South Wolcott Avenue Chicago, IL, United States of America

http://orcid.org/0000-0003-2925-8235

⨯
Rasha E. Shalaby,

Affiliation Department of Microbiology and Immunology College of Medicine University of Illinois at Chicago 909 South Wolcott Avenue Chicago, IL, United States of America
⨯
Saira Iram,

Affiliation Department of Microbiology and Immunology College of Medicine University of Illinois at Chicago 909 South Wolcott Avenue Chicago, IL, United States of America
⨯
Claudia E. Oropeza,

Affiliation Department of Microbiology and Immunology College of Medicine University of Illinois at Chicago 909 South Wolcott Avenue Chicago, IL, United States of America
⨯
Jennifer A. Landolfi,

Affiliation Toxicology Research Laboratory Department of Pharmacology College of Medicine University of Illinois at Chicago Chicago, IL, United States of America
⨯
Alexander V. Lyubimov,

Affiliation Toxicology Research Laboratory Department of Pharmacology College of Medicine University of Illinois at Chicago Chicago, IL, United States of America
⨯
Mark Maienschein-Cline,

Affiliation Research Resources Center College of Medicine University of Illinois at Chicago 835 South Wolcott Avenue Chicago, IL, United States of America
⨯
Stefan J. Green,

Affiliation Research Resources Center College of Medicine University of Illinois at Chicago 835 South Wolcott Avenue Chicago, IL, United States of America

http://orcid.org/0000-0003-2781-359X

⨯
Klaus H. Kaestner,

Affiliation Department of Genetics University of Pennsylvania School of Medicine Philadelphia, PA, United States of America
⨯
Alan McLachlan

* E-mail: mclach@uic.edu

Affiliation Department of Microbiology and Immunology College of Medicine University of Illinois at Chicago 909 South Wolcott Avenue Chicago, IL, United States of America

http://orcid.org/0000-0002-4168-2365

⨯

Hepatic deficiency of the pioneer transcription factor FoxA restricts hepatitis B virus biosynthesis by the developmental regulation of viral DNA methylation

Vanessa C. McFadden,
Rasha E. Shalaby,
Saira Iram,
Claudia E. Oropeza,
Jennifer A. Landolfi,
Alexander V. Lyubimov,
Mark Maienschein-Cline,
Stefan J. Green,
Klaus H. Kaestner,
Alan McLachlan

Published: February 24, 2017
https://doi.org/10.1371/journal.ppat.1006239

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