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Open Access
Peer-reviewed
Research Article
Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication
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Eveline Kindler,
Affiliations Department of Infectious Diseases and Pathobiology, University of Bern, Bern, Switzerland, Federal Department of Home Affairs, Institute of Virology and Immunology, Bern and Mittelhäusern, Switzerland
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Cristina Gil-Cruz,
Affiliation Institute of Immunobiology, Kantonsspital St.Gallen, St.Gallen, Switzerland
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Julia Spanier,
Affiliation Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research and the Hannover Medical School, Hannover, Germany
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Yize Li,
Affiliation Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America
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Jochen Wilhelm,
Affiliation Universities Giessen & Marburg Lung Center (UGMLC), Deutsches Zentrum für Lungenforschung (DZL), Giessen, Germany
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Huib H. Rabouw,
Affiliation Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
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Roland Züst,
Affiliation Singapore Immunology Network, Singapore
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Mihyun Hwang,
Affiliation Department of Neurosciences, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio, United States of America
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Philip V’kovski,
Affiliations Department of Infectious Diseases and Pathobiology, University of Bern, Bern, Switzerland, Federal Department of Home Affairs, Institute of Virology and Immunology, Bern and Mittelhäusern, Switzerland, Graduate School for Biomedical Science, University of Bern, Bern, Switzerland
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Hanspeter Stalder,
Affiliations Department of Infectious Diseases and Pathobiology, University of Bern, Bern, Switzerland, Federal Department of Home Affairs, Institute of Virology and Immunology, Bern and Mittelhäusern, Switzerland
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Sabrina Marti,
Affiliations Department of Infectious Diseases and Pathobiology, University of Bern, Bern, Switzerland, Federal Department of Home Affairs, Institute of Virology and Immunology, Bern and Mittelhäusern, Switzerland
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Matthias Habjan,
Affiliation Max-Planck-Institute of Biochemistry, Martinsried, Germany
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Luisa Cervantes-Barragan,
Affiliation Washington University School of Medicine, St. Louis, MO, USA
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Ruth Elliot,
Affiliation Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America
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Nadja Karl,
Affiliation Institute for Medical Virology, Justus-Liebig-University, Giessen, Germany
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Christina Gaughan,
Affiliation Department of Cancer Biology, Lerner Research Institute, Cleveland, Ohio, United States of America
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Frank J. M. van Kuppeveld,
Affiliation Virology Division, Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands
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Robert H. Silverman,
Affiliation Department of Cancer Biology, Lerner Research Institute, Cleveland, Ohio, United States of America
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Markus Keller,
Affiliation Institute of Novel and Emerging Infectious Diseases, Friedrich-Loeffler-Institut, Greifswald-Insel Riems, Germany
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Burkhard Ludewig,
Affiliation Institute of Immunobiology, Kantonsspital St.Gallen, St.Gallen, Switzerland
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Cornelia C. Bergmann,
Affiliation Department of Neurosciences, Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, Ohio, United States of America
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John Ziebuhr,
Affiliation Institute for Medical Virology, Justus-Liebig-University, Giessen, Germany
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Susan R. Weiss,
Affiliation Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States of America
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Ulrich Kalinke,
Affiliation Institute for Experimental Infection Research, TWINCORE, Centre for Experimental and Clinical Infection Research, a joint venture between the Helmholtz Centre for Infection Research and the Hannover Medical School, Hannover, Germany
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Volker Thiel
* E-mail: Volker.thiel@vetsuisse.unibe.ch
Affiliations Department of Infectious Diseases and Pathobiology, University of Bern, Bern, Switzerland, Federal Department of Home Affairs, Institute of Virology and Immunology, Bern and Mittelhäusern, Switzerland
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Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replication
- Eveline Kindler,
- Cristina Gil-Cruz,
- Julia Spanier,
- Yize Li,
- Jochen Wilhelm,
- Huib H. Rabouw,
- Roland Züst,
- Mihyun Hwang,
- Philip V’kovski,
- Hanspeter Stalder
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- Published: February 3, 2017
- https://doi.org/10.1371/journal.ppat.1006195