An Oxygen-Sensing Two-Component System in the Burkholderia cepacia Complex Regulates Biofilm, Intracellular Invasion, and Pathogenicity

• Matthew M. Schaefers ,

  * E-mail: matthew.schaefers@childrens.harvard.edu

  Affiliations Division of Critical Care Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children’s Hospital, Boston, Massachusetts, United States of America, Department of Anaesthesia, Harvard Medical School, Boston, Massachusetts, United States of America

  http://orcid.org/0000-0001-7454-4180

  ⨯
• Tiffany L. Liao,

  Affiliation Division of Critical Care Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children’s Hospital, Boston, Massachusetts, United States of America

  ⨯
• Nicole M. Boisvert,

  Affiliation Division of Critical Care Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children’s Hospital, Boston, Massachusetts, United States of America

  ⨯
• Damien Roux,

  Affiliation IAME, UMR 1137, INSERM, Université Paris Diderot, Sorbonne Paris Cité, Paris, France; Service de Réanimation médico-chirurgicale, Hôpital Louis Mourier, AP-HP, Colombes, France

  http://orcid.org/0000-0002-6103-6416

  ⨯
• Deborah Yoder-Himes,

  Affiliation Department of Biology, University of Louisville, Louisville, Kentucky, United States of America

  http://orcid.org/0000-0001-9576-3833

  ⨯
• Gregory P. Priebe

  Affiliations Division of Critical Care Medicine, Department of Anesthesiology, Perioperative and Pain Medicine, Boston Children’s Hospital, Boston, Massachusetts, United States of America, Department of Anaesthesia, Harvard Medical School, Boston, Massachusetts, United States of America

  ⨯