Persistent Low-Level Replication of SIVΔnef Drives Maturation of Antibody and CD8 T Cell Responses to Induce Protective Immunity against Vaginal SIV Infection

• Sama Adnan ,

  Contributed equally to this work with: Sama Adnan, R. Keith Reeves

  Affiliations Yerkes National Primate Research Center, Emory University, Atlanta GA, United States of America, New England Primate Research Center, Harvard Medical School, Southborough Campus, Pine Hill Drive, Southborough, MA, United States of America

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• R. Keith Reeves ,

  Contributed equally to this work with: Sama Adnan, R. Keith Reeves

  Affiliations New England Primate Research Center, Harvard Medical School, Southborough Campus, Pine Hill Drive, Southborough, MA, United States of America, Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Boston, MA, United States of America

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• Jacqueline Gillis,

  Affiliation New England Primate Research Center, Harvard Medical School, Southborough Campus, Pine Hill Drive, Southborough, MA, United States of America

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• Fay E. Wong,

  Affiliation New England Primate Research Center, Harvard Medical School, Southborough Campus, Pine Hill Drive, Southborough, MA, United States of America

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• Yi Yu,

  Affiliation New England Primate Research Center, Harvard Medical School, Southborough Campus, Pine Hill Drive, Southborough, MA, United States of America

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• Jeremy V. Camp,

  Affiliation Department of Microbiology, Immunology and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America

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• Qingsheng Li,

  Affiliation Nebraska Center for Virology and School of Biological Sciences, University of Nebraska-Lincoln, Lincoln, Nebraska, United States of America

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• Michelle Connole,

  Affiliation New England Primate Research Center, Harvard Medical School, Southborough Campus, Pine Hill Drive, Southborough, MA, United States of America

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• Yuan Li,

  Affiliation AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America

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• Michael Piatak Jr †,

  † Deceased.

  Affiliation AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America

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• Jeffrey D. Lifson,

  Affiliation AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America

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• Wenjun Li,

  Affiliation Department of Medicine, University of Massachusetts Medical School, Worcester, MA, United States of America

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• Brandon F. Keele,

  Affiliation AIDS and Cancer Virus Program, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland, United States of America

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• Pamela A. Kozlowski,

  Affiliation Department of Microbiology, Immunology and Parasitology, Louisiana State University Health Sciences Center, New Orleans, Louisiana, United States of America

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• Ronald C. Desrosiers,

  Affiliation Department of Pathology, University of Miami Miller School of Medicine, Miami, Florida, United States of America

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• Ashley T. Haase,

  Affiliation Department of Microbiology, Medical School, University of Minnesota, MMC 196, 420 Delaware Street S.E., Minneapolis, Minnesota, United States of America

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•  [ ... ],
• R. Paul Johnson

  * E-mail: rpaul.johnson@emory.edu

  Affiliations Yerkes National Primate Research Center, Emory University, Atlanta GA, United States of America, New England Primate Research Center, Harvard Medical School, Southborough Campus, Pine Hill Drive, Southborough, MA, United States of America, Ragon Institute of MGH, MIT and Harvard, Cambridge, MA, United States of America

  http://orcid.org/0000-0002-2600-120X

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