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A Novel Zn2-Cys6 Transcription Factor AtrR Plays a Key Role in an Azole Resistance Mechanism of Aspergillus fumigatus by Co-regulating cyp51A and cdr1B Expressions
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Daisuke Hagiwara ,
Contributed equally to this work with: Daisuke Hagiwara, Daisuke Miura
* E-mail: dhagi@chiba-u.jp (DH); gomi@biochem.tohoku.ac.jp (KG)
Affiliation Medical Mycology Research Center, Chiba University, Chiba, Japan
⨯ - Daisuke Miura ,
- Kiminori Shimizu,
- Sanjoy Paul,
- Ayumi Ohba,
- Tohru Gonoi,
- Akira Watanabe,
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Katsuhiko Kamei,
Affiliation Medical Mycology Research Center, Chiba University, Chiba, Japan
⨯ -
Takahiro Shintani,
Affiliation Department of Bioindustrial Informatics and Genomics, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan
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W. Scott Moye-Rowley,
Affiliation Department of Molecular Physiology and Biophysics, Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States of America
⨯ -
Susumu Kawamoto,
Affiliation Medical Mycology Research Center, Chiba University, Chiba, Japan
⨯ - Katsuya Gomi
http://orcid.org/0000-0003-1382-3914
A Novel Zn2-Cys6 Transcription Factor AtrR Plays a Key Role in an Azole Resistance Mechanism of Aspergillus fumigatus by Co-regulating cyp51A and cdr1B Expressions
- Daisuke Hagiwara,
- Daisuke Miura,
- Kiminori Shimizu,
- Sanjoy Paul,
- Ayumi Ohba,
- Tohru Gonoi,
- Akira Watanabe,
- Katsuhiko Kamei,
- Takahiro Shintani,
- W. Scott Moye-Rowley
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- Published: January 4, 2017
- https://doi.org/10.1371/journal.ppat.1006096