Effective Respiratory CD8 T-Cell Immunity to Influenza Virus Induced by Intranasal Carbomer-Lecithin-Adjuvanted Non-replicating Vaccines

David J. Gasper; Brandon Neldner; Erin H. Plisch; Hani Rustom; Emily Carrow; Hirotaka Imai; Yoshihiro Kawaoka; M. Suresh

doi:10.1371/journal.ppat.1006064

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Open Access

Peer-reviewed

Research Article

Effective Respiratory CD8 T-Cell Immunity to Influenza Virus Induced by Intranasal Carbomer-Lecithin-Adjuvanted Non-replicating Vaccines

David J. Gasper,

Current Address: Pacific Zoo & Wildlife Diagnostics, San Diego, California, United States of America

Affiliations Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Comparative Biomedical Sciences Graduate Program, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
⨯
Brandon Neldner,

Affiliation Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
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Erin H. Plisch,

Affiliation Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
⨯
Hani Rustom,

Affiliation Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
⨯
Emily Carrow,

Affiliation Advanced Bioadjuvants, Omaha, Nebraska, United States of America

http://orcid.org/0000-0002-4799-5637

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Hirotaka Imai,

Affiliation Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
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Yoshihiro Kawaoka,

Affiliation Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
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M. Suresh

* E-mail: sureshm@vetmed.wisc.edu

Affiliation Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, United States of America
⨯

Effective Respiratory CD8 T-Cell Immunity to Influenza Virus Induced by Intranasal Carbomer-Lecithin-Adjuvanted Non-replicating Vaccines

David J. Gasper,
Brandon Neldner,
Erin H. Plisch,
Hani Rustom,
Emily Carrow,
Hirotaka Imai,
Yoshihiro Kawaoka,
M. Suresh

Published: December 20, 2016
https://doi.org/10.1371/journal.ppat.1006064

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