Cytomegalovirus-Specific IL-10-Producing CD4⁺ T Cells Are Governed by Type-I IFN-Induced IL-27 and Promote Virus Persistence

• Mathew Clement ,

  * E-mail: Clementm@cf.ac.uk (MC); humphreysir@cf.ac.uk (IRH)

  Affiliation Division of Infection & Immunity, Cardiff University, Cardiff, United Kingdom

  http://orcid.org/0000-0002-9280-5281

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• Morgan Marsden,

  Affiliation Division of Infection & Immunity, Cardiff University, Cardiff, United Kingdom

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• Maria A. Stacey,

  Affiliation Division of Infection & Immunity, Cardiff University, Cardiff, United Kingdom

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• Juneid Abdul-Karim,

  Affiliation Division of Infection & Immunity, Cardiff University, Cardiff, United Kingdom

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• Silvia Gimeno Brias,

  Affiliation Division of Infection & Immunity, Cardiff University, Cardiff, United Kingdom

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• Diana Costa Bento,

  Affiliation Division of Infection & Immunity, Cardiff University, Cardiff, United Kingdom

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• Martin J. Scurr,

  Affiliation Division of Infection & Immunity, Cardiff University, Cardiff, United Kingdom

  http://orcid.org/0000-0002-4120-0688

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• Peter Ghazal,

  Affiliation Division of Infection and Pathway Medicine, University of Edinburgh, Edinburgh, United Kingdom

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• Casey T. Weaver,

  Affiliation Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, United States of America

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• Gianluca Carlesso,

  Affiliation Respiratory, Inflammation and Autoimmunity, Research Department, MedImmune LLC, Gaithersburg, MD, United States of America

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• Simon Clare,

  Affiliation Wellcome Trust Sanger Institute, Cambridgeshire, United Kingdom

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• Simon A. Jones,

  Affiliation Division of Infection & Immunity, Cardiff University, Cardiff, United Kingdom

  http://orcid.org/0000-0001-7297-9711

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• Andrew Godkin,

  Affiliation Division of Infection & Immunity, Cardiff University, Cardiff, United Kingdom

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• Gareth W. Jones,

  Affiliation Division of Infection & Immunity, Cardiff University, Cardiff, United Kingdom

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• Ian R. Humphreys

  * E-mail: Clementm@cf.ac.uk (MC); humphreysir@cf.ac.uk (IRH)

  Affiliations Division of Infection & Immunity, Cardiff University, Cardiff, United Kingdom, Wellcome Trust Sanger Institute, Cambridgeshire, United Kingdom

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