The L-Arginine Transporter Solute Carrier Family 7 Member 2 Mediates the Immunopathogenesis of Attaching and Effacing Bacteria

Kshipra Singh; Nicole T. Al-Greene; Thomas G. Verriere; Lori A. Coburn; Mohammad Asim; Daniel P. Barry; Margaret M. Allaman; Dana M. Hardbower; Alberto G. Delgado; M. Blanca Piazuelo; Bruce A. Vallance; Alain P. Gobert; Keith T. Wilson

doi:10.1371/journal.ppat.1005984

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Peer-reviewed

Research Article

The L-Arginine Transporter Solute Carrier Family 7 Member 2 Mediates the Immunopathogenesis of Attaching and Effacing Bacteria

Kshipra Singh,

Affiliation Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
⨯
Nicole T. Al-Greene,

Affiliation Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

http://orcid.org/0000-0003-2855-1317

⨯
Thomas G. Verriere,

Affiliation Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
⨯
Lori A. Coburn,

Affiliations Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Center for Mucosal Inflammation and Cancer, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, United States of America
⨯
Mohammad Asim,

Affiliation Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
⨯
Daniel P. Barry,

Affiliation Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

http://orcid.org/0000-0002-3972-3914

⨯
Margaret M. Allaman,

Affiliation Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
⨯
Dana M. Hardbower,

Affiliations Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
⨯
Alberto G. Delgado,

Affiliation Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
⨯
M. Blanca Piazuelo,

Affiliation Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

http://orcid.org/0000-0002-0000-1324

⨯
Bruce A. Vallance,

Affiliation Division of Gastroenterology, Department of Pediatrics, Child and Family Research Institute, University of British Columbia, Vancouver, British Columbia, Canada
⨯
Alain P. Gobert,

Affiliations Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Center for Mucosal Inflammation and Cancer, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
⨯
Keith T. Wilson

* E-mail: keith.wilson@vanderbilt.edu

Affiliations Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Center for Mucosal Inflammation and Cancer, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Veterans Affairs Tennessee Valley Healthcare System, Nashville, Tennessee, United States of America, Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
⨯

The L-Arginine Transporter Solute Carrier Family 7 Member 2 Mediates the Immunopathogenesis of Attaching and Effacing Bacteria

Kshipra Singh,
Nicole T. Al-Greene,
Thomas G. Verriere,
Lori A. Coburn,
Mohammad Asim,
Daniel P. Barry,
Margaret M. Allaman,
Dana M. Hardbower,
Alberto G. Delgado,
M. Blanca Piazuelo

Published: October 26, 2016
https://doi.org/10.1371/journal.ppat.1005984

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