Sphingosine 1-Phosphate Activation of EGFR As a Novel Target for Meningitic Escherichia coli Penetration of the Blood-Brain Barrier

• Xiangru Wang,

  Affiliations Department of Pediatrics, Division of Pediatric Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America, State Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China

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• Ravi Maruvada,

  Affiliation Department of Pediatrics, Division of Pediatric Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Andrew J. Morris,

  Affiliation Division of Cardiovascular Medicine, The Gill Heart Institute, University of Kentucky, Lexington, Kentucky, United States of America

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• Jun O. Liu,

  Affiliation Department of Pharmacology and Molecular Sciences, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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• Michael J. Wolfgang,

  Affiliation Department of Biological Chemistry, Center for Metabolism and Obesity Research, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

  http://orcid.org/0000-0003-2349-8414

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• Dong Jae Baek,

  Affiliation Department of Chemistry and Biochemistry, Queens College, The City University of New York, Flushing, New York, United States of America

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• Robert Bittman †,

  † Deceased.

  Affiliation Department of Chemistry and Biochemistry, Queens College, The City University of New York, Flushing, New York, United States of America

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• Kwang Sik Kim

  * E-mail: kwangkim@jhmi.edu

  Affiliation Department of Pediatrics, Division of Pediatric Infectious Diseases, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States of America

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