The Structure of Treponema pallidum Tp0751 (Pallilysin) Reveals a Non-canonical Lipocalin Fold That Mediates Adhesion to Extracellular Matrix Components and Interactions with Host Cells

• Michelle L. Parker ,

  Contributed equally to this work with: Michelle L. Parker, Simon Houston

  Affiliation Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada

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• Simon Houston ,

  Contributed equally to this work with: Michelle L. Parker, Simon Houston

  Affiliation Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada

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• Helena Pětrošová,

  Affiliation Matrix Dynamics Group, Faculty of Dentistry, Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

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• Karen V. Lithgow,

  Affiliation Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada

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• Rebecca Hof,

  Affiliation Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada

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• Charmaine Wetherell,

  Affiliation Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada

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• Wei-Chien Kao,

  Affiliation Matrix Dynamics Group, Faculty of Dentistry, Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

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• Yi-Pin Lin,

  Current address: Division of Infectious Diseases, Wadsworth Center, New York State Department of Health, Albany, New York, United States of America

  Affiliation Department of Molecular Biology and Microbiology, Tufts University School of Medicine, Boston, Massachusetts, United States of America

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• Tara J. Moriarty,

  Affiliation Matrix Dynamics Group, Faculty of Dentistry, Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

  http://orcid.org/0000-0002-1751-5145

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• Rhodaba Ebady,

  Affiliation Matrix Dynamics Group, Faculty of Dentistry, Department of Laboratory Medicine and Pathobiology, Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada

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• Caroline E. Cameron ,

  * E-mail: caroc@uvic.ca (CEC); mboulang@uvic.ca (MJB)

  Affiliation Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada

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• Martin J. Boulanger

  * E-mail: caroc@uvic.ca (CEC); mboulang@uvic.ca (MJB)

  Affiliation Department of Biochemistry and Microbiology, University of Victoria, Victoria, British Columbia, Canada

  http://orcid.org/0000-0001-6835-9309

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