Tbet Deficiency Causes T Helper Cell Dependent Airways Eosinophilia and Mucus Hypersecretion in Response to Rhinovirus Infection

Nicholas Glanville; Tamlyn J. Peel; Armin Schröder; Julia Aniscenko; Ross P. Walton; Susetta Finotto; Sebastian L. Johnston

doi:10.1371/journal.ppat.1005913

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Peer-reviewed

Research Article

Tbet Deficiency Causes T Helper Cell Dependent Airways Eosinophilia and Mucus Hypersecretion in Response to Rhinovirus Infection

Nicholas Glanville,

Affiliation Airway Disease Infection Section, National Heart and Lung Institute, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, Imperial College London, London, United Kingdom
⨯
Tamlyn J. Peel,

Current address: Centre for Molecular & Cellular Biology of Inflammation, Division of Immunology, Infection and Inflammatory Diseases, King’s College School of Medicine, Guy’s Campus, King’s College London, London, United Kingdom

Affiliation Airway Disease Infection Section, National Heart and Lung Institute, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, Imperial College London, London, United Kingdom

http://orcid.org/0000-0003-4188-612X

⨯
Armin Schröder,

Affiliation Laboratory of Cellular and Molecular Lung Immunology, Department of Molecular Pneumology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany
⨯
Julia Aniscenko,

Affiliation Airway Disease Infection Section, National Heart and Lung Institute, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, Imperial College London, London, United Kingdom

http://orcid.org/0000-0001-8641-1123

⨯
Ross P. Walton,

Affiliation Airway Disease Infection Section, National Heart and Lung Institute, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, Imperial College London, London, United Kingdom
⨯
Susetta Finotto,

Affiliation Laboratory of Cellular and Molecular Lung Immunology, Department of Molecular Pneumology, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany

http://orcid.org/0000-0001-7623-7977

⨯
Sebastian L. Johnston

* E-mail: s.johnston@imperial.ac.uk

Affiliation Airway Disease Infection Section, National Heart and Lung Institute, MRC & Asthma UK Centre in Allergic Mechanisms of Asthma, Imperial College London, London, United Kingdom
⨯

Tbet Deficiency Causes T Helper Cell Dependent Airways Eosinophilia and Mucus Hypersecretion in Response to Rhinovirus Infection

Nicholas Glanville,
Tamlyn J. Peel,
Armin Schröder,
Julia Aniscenko,
Ross P. Walton,
Susetta Finotto,
Sebastian L. Johnston

Published: September 28, 2016
https://doi.org/10.1371/journal.ppat.1005913

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