DNA Polymerase κ Is a Key Cellular Factor for the Formation of Covalently Closed Circular DNA of Hepatitis B Virus

Yonghe Qi; Zhenchao Gao; Guangwei Xu; Bo Peng; Chenxuan Liu; Huan Yan; Qiyan Yao; Guoliang Sun; Yang Liu; Dingbin Tang; Zilin Song; Wenhui He; Yinyan Sun; Ju-Tao Guo; Wenhui Li

doi:10.1371/journal.ppat.1005893

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Open Access

Peer-reviewed

Research Article

DNA Polymerase κ Is a Key Cellular Factor for the Formation of Covalently Closed Circular DNA of Hepatitis B Virus

Yonghe Qi,

Affiliation National Institute of Biological Sciences, Beijing, China
⨯
Zhenchao Gao,

Affiliations National Institute of Biological Sciences, Beijing, China, Graduate program in School of Life Sciences, Peking University, Beijing, China
⨯
Guangwei Xu,

Affiliation National Institute of Biological Sciences, Beijing, China

http://orcid.org/0000-0003-3350-5147

⨯
Bo Peng,

Affiliations National Institute of Biological Sciences, Beijing, China, Graduate program in School of Life Sciences, Peking University, Beijing, China
⨯
Chenxuan Liu,

Affiliations National Institute of Biological Sciences, Beijing, China, College of Life Sciences Beijing Normal University, Beijing, China

http://orcid.org/0000-0002-9960-1302

⨯
Huan Yan,

Affiliation National Institute of Biological Sciences, Beijing, China
⨯
Qiyan Yao,

Affiliation National Institute of Biological Sciences, Beijing, China

http://orcid.org/0000-0001-7253-0420

⨯
Guoliang Sun,

Affiliation National Institute of Biological Sciences, Beijing, China

http://orcid.org/0000-0001-5403-5741

⨯
Yang Liu,

Affiliations National Institute of Biological Sciences, Beijing, China, School of Life Science, Tsinghua University, Beijing, China

http://orcid.org/0000-0002-4952-7714

⨯
Dingbin Tang,

Affiliations National Institute of Biological Sciences, Beijing, China, Graduate program in School of Life Sciences, Peking University, Beijing, China
⨯
Zilin Song,

Affiliation National Institute of Biological Sciences, Beijing, China
⨯
Wenhui He,

Affiliation National Institute of Biological Sciences, Beijing, China
⨯
Yinyan Sun,

Affiliation National Institute of Biological Sciences, Beijing, China
⨯
Ju-Tao Guo,

Affiliation Baruch S. Blumberg Institute, Doylestown, Pennsylvania, United States of America
⨯
Wenhui Li

* E-mail: liwenhui@nibs.ac.cn (WL)

Affiliation National Institute of Biological Sciences, Beijing, China
⨯

DNA Polymerase κ Is a Key Cellular Factor for the Formation of Covalently Closed Circular DNA of Hepatitis B Virus

Yonghe Qi,
Zhenchao Gao,
Guangwei Xu,
Bo Peng,
Chenxuan Liu,
Huan Yan,
Qiyan Yao,
Guoliang Sun,
Yang Liu,
Dingbin Tang

Published: October 26, 2016
https://doi.org/10.1371/journal.ppat.1005893

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Small interfering RNA
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DNA polymerase
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Hepatitis B virus
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DNA synthesis
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