Immune-Complexed Adenovirus Induce AIM2-Mediated Pyroptosis in Human Dendritic Cells

Karsten Eichholz; Thierry Bru; Thi Thu Phuong Tran; Paulo Fernandes; Hugh Welles; Franck J. D. Mennechet; Nicolas Manel; Paula Alves; Matthieu Perreau; Eric J. Kremer

doi:10.1371/journal.ppat.1005871

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Peer-reviewed

Research Article

Immune-Complexed Adenovirus Induce AIM2-Mediated Pyroptosis in Human Dendritic Cells

Karsten Eichholz,

Affiliations Institut de Génétique Moléculaire de Montpellier, CNRS 5535, Montpellier, France, Université de Montpellier, Montpellier, France
⨯
Thierry Bru,

Affiliations Institut de Génétique Moléculaire de Montpellier, CNRS 5535, Montpellier, France, Université de Montpellier, Montpellier, France
⨯
Thi Thu Phuong Tran,

Affiliations Institut de Génétique Moléculaire de Montpellier, CNRS 5535, Montpellier, France, Université de Montpellier, Montpellier, France
⨯
Paulo Fernandes,

Affiliations iBET- Instituto de Biologia Experimental e Tecnológica, Oeiras, Portugal, Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal
⨯
Hugh Welles,

Affiliation Division of Immunology and Allergy, University of Lausanne, Lausanne, Switzerland

http://orcid.org/0000-0002-3336-1203

⨯
Franck J. D. Mennechet,

Affiliations Institut de Génétique Moléculaire de Montpellier, CNRS 5535, Montpellier, France, Université de Montpellier, Montpellier, France
⨯
Nicolas Manel,

Affiliation Institut Curie, INSERM U932, Paris, France
⨯
Paula Alves,

Affiliations iBET- Instituto de Biologia Experimental e Tecnológica, Oeiras, Portugal, Instituto de Tecnologia Química e Biológica, Universidade Nova de Lisboa, Oeiras, Portugal
⨯
Matthieu Perreau,

Affiliation Division of Immunology and Allergy, University of Lausanne, Lausanne, Switzerland
⨯
Eric J. Kremer

* E-mail: eric.kremer@igmm.cnrs.fr

Affiliations Institut de Génétique Moléculaire de Montpellier, CNRS 5535, Montpellier, France, Université de Montpellier, Montpellier, France

http://orcid.org/0000-0001-6114-7530

⨯

Immune-Complexed Adenovirus Induce AIM2-Mediated Pyroptosis in Human Dendritic Cells

Karsten Eichholz,
Thierry Bru,
Thi Thu Phuong Tran,
Paulo Fernandes,
Hugh Welles,
Franck J. D. Mennechet,
Nicolas Manel,
Paula Alves,
Matthieu Perreau,
Eric J. Kremer

Published: September 16, 2016
https://doi.org/10.1371/journal.ppat.1005871

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