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Open Access
Peer-reviewed
Research Article
MIF-Mediated Hemodilution Promotes Pathogenic Anemia in Experimental African Trypanosomosis
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Benoît Stijlemans ,
* E-mail: bstijlem@vub.ac.be
Affiliations Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium, Lab of Myeloid Cell Immunology, VIB Inflammation Research Center, Ghent, Belgium
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Lea Brys,
Affiliations Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium, Lab of Myeloid Cell Immunology, VIB Inflammation Research Center, Ghent, Belgium
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Hannelie Korf,
Affiliation Translational Research Center for Gastrointestinal Disorders (TARGID), Department of Clinical and Experimental Medicine, KU Leuven, Leuven, Belgium
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Pawel Bieniasz-Krzywiec,
Affiliation VIB Vesalius Research Center, University of Leuven (KUL), Leuven, Belgium
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Amanda Sparkes,
Affiliations Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium, Lab of Myeloid Cell Immunology, VIB Inflammation Research Center, Ghent, Belgium
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Liese Vansintjan,
Affiliations Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium, Lab of Myeloid Cell Immunology, VIB Inflammation Research Center, Ghent, Belgium
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Lin Leng,
Affiliation Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, United States of America
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Nele Vanbekbergen,
Affiliation Laboratorium Cellulaire Genetica (CEGE), Vrije Universiteit Brussel (VUB), Brussels, Belgium
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Massimiliano Mazzone,
Affiliation VIB Vesalius Research Center, University of Leuven (KUL), Leuven, Belgium
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Guy Caljon,
Affiliations Laboratory for Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Wilrijk, Belgium, Unit of Veterinary Protozoology, Department of Biomedical Sciences, Institute of Tropical Medicine Antwerp (ITM), Antwerp, Belgium
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Jan Van Den Abbeele,
Affiliation Unit of Veterinary Protozoology, Department of Biomedical Sciences, Institute of Tropical Medicine Antwerp (ITM), Antwerp, Belgium
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Steven Odongo,
Affiliations Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium, Department of Structural Biology, Vrije Universiteit Brussel, Brussels, Belgium
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Carl De Trez,
Affiliations Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium, Department of Structural Biology, Vrije Universiteit Brussel, Brussels, Belgium
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Stefan Magez,
Affiliations Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium, Department of Structural Biology, Vrije Universiteit Brussel, Brussels, Belgium, Laboratory for Biomedical Research, Ghent University Global Campus, Yeonsu-Gu, Incheon, South Korea
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Jo A. Van Ginderachter,
Affiliations Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium, Lab of Myeloid Cell Immunology, VIB Inflammation Research Center, Ghent, Belgium
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Alain Beschin ,
¶‡ These authors are joint last authors on this work.
Affiliations Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium, Lab of Myeloid Cell Immunology, VIB Inflammation Research Center, Ghent, Belgium
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Richard Bucala ,
¶‡ These authors are joint last authors on this work.
Affiliation Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, United States of America
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Patrick De Baetselier
¶‡ These authors are joint last authors on this work.
Affiliations Laboratory of Cellular and Molecular Immunology, Vrije Universiteit Brussel (VUB), Brussels, Belgium, Lab of Myeloid Cell Immunology, VIB Inflammation Research Center, Ghent, Belgium
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MIF-Mediated Hemodilution Promotes Pathogenic Anemia in Experimental African Trypanosomosis
- Benoît Stijlemans,
- Lea Brys,
- Hannelie Korf,
- Pawel Bieniasz-Krzywiec,
- Amanda Sparkes,
- Liese Vansintjan,
- Lin Leng,
- Nele Vanbekbergen,
- Massimiliano Mazzone,
- Guy Caljon
- Published: September 15, 2016
- https://doi.org/10.1371/journal.ppat.1005862