Francisella tularensis IglG Belongs to a Novel Family of PAAR-Like T6SS Proteins and Harbors a Unique N-terminal Extension Required for Virulence

• Mélanie Rigard ,

  Contributed equally to this work with: Mélanie Rigard, Jeanette E. Bröms

  Affiliations CIRI, International Center for Infectiology Research, Inserm U1111, CNRS, UMR5308, Lyon, France, University of Lyon, Lyon, France, Ecole Normale Supérieure de Lyon, Lyon, France

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• Jeanette E. Bröms ,

  Contributed equally to this work with: Mélanie Rigard, Jeanette E. Bröms

  Affiliation Department of Clinical Microbiology, Clinical Bacteriology, and Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden

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• Amandine Mosnier,

  Affiliations CIRI, International Center for Infectiology Research, Inserm U1111, CNRS, UMR5308, Lyon, France, University of Lyon, Lyon, France, Ecole Normale Supérieure de Lyon, Lyon, France

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• Maggy Hologne,

  Affiliation Institut des Sciences Analytiques, CNRS, UMR 5280, Université de Lyon, Université Claude Bernard Lyon 1, ENS de Lyon, Villeurbanne, France

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• Amandine Martin,

  Affiliations CIRI, International Center for Infectiology Research, Inserm U1111, CNRS, UMR5308, Lyon, France, University of Lyon, Lyon, France, Ecole Normale Supérieure de Lyon, Lyon, France

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• Lena Lindgren,

  Affiliation Department of Clinical Microbiology, Clinical Bacteriology, and Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden

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• Claire Punginelli,

  Affiliations CIRI, International Center for Infectiology Research, Inserm U1111, CNRS, UMR5308, Lyon, France, University of Lyon, Lyon, France, Ecole Normale Supérieure de Lyon, Lyon, France

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• Claire Lays,

  Affiliations CIRI, International Center for Infectiology Research, Inserm U1111, CNRS, UMR5308, Lyon, France, University of Lyon, Lyon, France, Ecole Normale Supérieure de Lyon, Lyon, France

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• Olivier Walker,

  Affiliation Institut des Sciences Analytiques, CNRS, UMR 5280, Université de Lyon, Université Claude Bernard Lyon 1, ENS de Lyon, Villeurbanne, France

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• Alain Charbit,

  Affiliations Université Paris Descartes, Sorbonne Paris Cité, Bâtiment Leriche, Paris, France, Institut Necker-Enfants Malades, Equipe 11: Pathogénie des Infections Systémiques, Paris, France

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• Philippe Telouk,

  Affiliations University of Lyon, Lyon, France, Laboratoire de Geologie de Lyon; Ecole Normale Supérieure de Lyon, Lyon, France

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• Wayne Conlan,

  Affiliation National Research Council Canada, Human Health Therapeutics Portfolio, Ottawa, Ontario, Canada

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• Laurent Terradot ,

  * E-mail: laurent.terradot@ibcp.fr (LT); anders.Sjostedt@umu.se (AS); thomas.henry@inserm.fr (TH)

  Affiliation Molecular Microbiology and Structural Biochemistry, UMR 5086, CNRS-Université de Lyon, Institut de Biologie et Chimie des Protéines, Lyon, France

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• Anders Sjöstedt ,

  * E-mail: laurent.terradot@ibcp.fr (LT); anders.Sjostedt@umu.se (AS); thomas.henry@inserm.fr (TH)

  Affiliation Department of Clinical Microbiology, Clinical Bacteriology, and Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, Umeå, Sweden

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• Thomas Henry

  * E-mail: laurent.terradot@ibcp.fr (LT); anders.Sjostedt@umu.se (AS); thomas.henry@inserm.fr (TH)

  Affiliations CIRI, International Center for Infectiology Research, Inserm U1111, CNRS, UMR5308, Lyon, France, University of Lyon, Lyon, France, Ecole Normale Supérieure de Lyon, Lyon, France

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