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Open Access
Peer-reviewed
Research Article
An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory Pathogens
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Victoria A. Meliopoulos ,
Contributed equally to this work with: Victoria A. Meliopoulos, Lee-Ann Van de Velde
Affiliation Department of Infectious Diseases, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
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Lee-Ann Van de Velde ,
Contributed equally to this work with: Victoria A. Meliopoulos, Lee-Ann Van de Velde
Affiliations Department of Infectious Diseases, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America, Department of Immunology, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
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Nicholas C. Van de Velde,
Affiliations Department of Infectious Diseases, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America, Department of Immunology, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
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Erik A. Karlsson,
Affiliation Department of Infectious Diseases, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
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Geoff Neale,
Affiliation The Hartwell Center, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
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Peter Vogel,
Affiliation Department of Veterinary Pathology Core, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
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Cliff Guy,
Affiliation Department of Immunology, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
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Shalini Sharma,
Affiliation Department of Immunology, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
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Susu Duan,
Affiliation Department of Immunology, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
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Sherri L. Surman,
Affiliation Department of Infectious Diseases, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
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Bart G. Jones,
Affiliation Department of Infectious Diseases, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
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Michael D. L. Johnson,
Affiliation Department of Infectious Diseases, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
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Catharine Bosio,
Affiliation Rocky Mountain Laboratories, NIAID, NIH, Hamilton, Montana, United States of America
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Lisa Jolly,
Affiliation Division of Respiratory Medicine, University of Nottingham, Nottingham, United Kingdom
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R. Gisli Jenkins,
Affiliation Division of Respiratory Medicine, University of Nottingham, Nottingham, United Kingdom
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Julia L. Hurwitz,
Affiliation Department of Infectious Diseases, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
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Jason W. Rosch,
Affiliation Department of Infectious Diseases, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
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Dean Sheppard,
Affiliation Department of Medicine, Division of Pulmonary, Critical Care, Allergy, and Sleep Medicine, UCSF Medical Center, San Francisco, California, United States of America
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Paul G. Thomas,
Affiliation Department of Immunology, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
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Peter J. Murray ,
* E-mail: peter.murray@stjude.org (PJM); Stacey.Schultz-Cherry@stjude.org (SSC)
Affiliations Department of Infectious Diseases, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America, Department of Immunology, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
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Stacey Schultz-Cherry
* E-mail: peter.murray@stjude.org (PJM); Stacey.Schultz-Cherry@stjude.org (SSC)
Affiliation Department of Infectious Diseases, St Jude Children’s Research Hospital, Memphis, Tennessee, United States of America
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An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory Pathogens
- Victoria A. Meliopoulos,
- Lee-Ann Van de Velde,
- Nicholas C. Van de Velde,
- Erik A. Karlsson,
- Geoff Neale,
- Peter Vogel,
- Cliff Guy,
- Shalini Sharma,
- Susu Duan,
- Sherri L. Surman
- Published: August 9, 2016
- https://doi.org/10.1371/journal.ppat.1005804