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Open Access
Peer-reviewed
Research Article
The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation
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Xiaowei Wang,
Affiliation Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
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Dana K. Shaw,
Affiliation Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
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Holly L. Hammond,
Affiliation Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
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Fayyaz S. Sutterwala,
Affiliation Division of Infectious Diseases, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
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Manira Rayamajhi,
Affiliation Department of Microbiology and Immunology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
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Kari Ann Shirey,
Affiliation Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
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Darren J. Perkins,
Affiliation Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
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Joseph V. Bonventre,
Affiliation Renal Division, Brigham and Women’s Hospital, Department of Medicine, Harvard Medical School, Boston, Massachusetts, United States of America
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Thangam S. Velayutham,
Affiliation Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America
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Sean M. Evans,
Affiliation Department of Microbiology and Immunology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America
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Kyle G. Rodino,
Affiliation Department of Microbiology and Immunology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America
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Lauren VieBrock,
Affiliation Department of Microbiology and Immunology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America
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Karen M. Scanlon,
Affiliation Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
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Nicholas H. Carbonetti,
Affiliation Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
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Jason A. Carlyon,
Affiliation Department of Microbiology and Immunology, Virginia Commonwealth University School of Medicine, Richmond, Virginia, United States of America
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Edward A. Miao,
Affiliation Department of Microbiology and Immunology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America
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Jere W. McBride,
Affiliation Department of Pathology, University of Texas Medical Branch, Galveston, Texas, United States of America
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Michail Kotsyfakis,
Affiliation Institute of Parasitology, Biology Centre, Czech Academy of Sciences, Budweis, Czech Republic
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Joao H. F. Pedra
* E-mail: jpedra@som.umaryland.edu
Affiliation Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America
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The Prostaglandin E2-EP3 Receptor Axis Regulates Anaplasma phagocytophilum-Mediated NLRC4 Inflammasome Activation
- Xiaowei Wang,
- Dana K. Shaw,
- Holly L. Hammond,
- Fayyaz S. Sutterwala,
- Manira Rayamajhi,
- Kari Ann Shirey,
- Darren J. Perkins,
- Joseph V. Bonventre,
- Thangam S. Velayutham,
- Sean M. Evans
- Published: August 2, 2016
- https://doi.org/10.1371/journal.ppat.1005803