Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond

• Wesley C. Van Voorhis ,

  * E-mail: wesley@uw.edu.

  Affiliation Departments of Medicine, Microbiology, and Global Health, Center for Emerging and Re-emerging Infectious Diseases (CERID) University of Washington, Seattle, Washington, United States of America

  ⨯
• John H. Adams,

  Affiliation Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida, United States of America

  ⨯
• Roberto Adelfio,

  Affiliations Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland

  ⨯
• Vida Ahyong,

  Affiliation Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of California, San Francisco, California, United States of America

  ⨯
• Myles H. Akabas,

  Affiliation Departments of Physiology & Biophysics, Neuroscience and Medicine, Albert Einstein College of Medicine, New York, New York, United States of America

  ⨯
• Pietro Alano,

  Affiliation Dipartimento Malattie Infettive, Parassitarie ed Immunomediate Istituto Superiore di Sanità, Roma, Italia

  ⨯
• Aintzane Alday,

  Affiliation BBD BioPhenix SL–BIOBIDE, Donostia, Gipuzkoa, Spain

  ⨯
• Yesmalie Alemán Resto,

  Affiliation Bigelow Laboratory for Ocean Sciences, East Boothbay, Maine, United States of America

  ⨯
• Aishah Alsibaee,

  Affiliation Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland

  ⨯
• Ainhoa Alzualde,

  Affiliation BBD BioPhenix SL–BIOBIDE, Donostia, Gipuzkoa, Spain

  ⨯
• Katherine T. Andrews,

  Affiliations Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia, QIMR Berghofer Medical Research Institute Herston, Brisbane, Australia

  ⨯
• Simon V. Avery,

  Affiliation School of Life Sciences, University of Nottingham, Nottingham, Nottinghamshire, England, United Kingdom

  ⨯
• Vicky M. Avery,

  Affiliation Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia

  ⨯
• Lawrence Ayong,

  Affiliation Institut Pasteur Korea, Pangyo Techno-Valley, Gyeonggi Province, Korea

  ⨯
• Mark Baker,

  Affiliation Clinical Pharmacology, Novartis Consumer Health, Nyon, Switzerland

  ⨯
• Stephen Baker,

  Affiliations Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, The Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam, Nuffield Department of Clinical Medicine, Centre for Tropical Medicine, Oxford University, Oxford, England, United Kingdom, The London School of Hygiene and Tropical Medicine, London, England, United Kingdom

  ⨯
• Choukri Ben Mamoun,

  Affiliation Internal Medicine, Yale University, New Haven, Connecticut, United States of America

  ⨯
• Sangeeta Bhatia,

  Affiliation Health Sciences and Technology/Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

  ⨯
• Quentin Bickle,

  Affiliation Department of Immunology & Infection, London School of Hygiene and Tropical Medicine, London, England, United Kingdom

  ⨯
• Lotfi Bounaadja,

  Affiliation Museum of National History, Sorbonne Universities, Paris, France

  ⨯
• Tana Bowling,

  Affiliation SCYNEXIS, Inc., Durham, North Carolina, United States of America

  ⨯
• Jürgen Bosch,

  Affiliation Department of Biochemistry and Molecular Biology and Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, Untied States of America

  ⨯
• Lauren E. Boucher,

  Affiliation Department of Biochemistry and Molecular Biology and Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, Untied States of America

  ⨯
• Fabrice F. Boyom,

  Affiliation Department of Biochemistry, University of Yaoundé, Yaoundé, Cameroon

  ⨯
• Jose Brea,

  Affiliation CIMUS Research Centre, University of Santiago de Compostela, Santiago de Compostela, A Coruña, Spain

  ⨯
• Marian Brennan,

  Affiliation Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland

  ⨯
• Audrey Burton,

  Affiliation SCYNEXIS, Inc., Durham, North Carolina, United States of America

  ⨯
• Conor R. Caffrey,

  Affiliation Center for Discovery and Innovation in Parasitic Diseases, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America

  ⨯
• Grazia Camarda,

  Affiliation Dipartimento Malattie Infettive, Parassitarie ed Immunomediate Istituto Superiore di Sanità, Roma, Italia

  ⨯
• Manuela Carrasquilla,

  Current address: Wellcome Trust Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, United Kingdom

  Affiliation Department of Biochemistry and Molecular Biology and Huck Center for Malaria Research, Pennsylvania State University, University Park, Pennsylvania, United States of America

  ⨯
• Dee Carter,

  Affiliation School of Life and Environmental Sciences, University of Sydney, Darlington New South Wales, Australia

  ⨯
• Maria Belen Cassera,

  Affiliation Department of Biochemistry and Virginia Tech Center for Drug Discovery, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, United States of America

  ⨯
• Ken Chih-Chien Cheng,

  Affiliation National Center of Advancing Translational Sciences, NIH, Bethesda, Maryland, United States of America

  ⨯
• Worathad Chindaudomsate,

  Affiliation Department of Biochemistry, Mahidol University, Bangkok, Thailand

  ⨯
• Anthony Chubb,

  Affiliation Molecular and Cellular Therapeutics, Royal College of Surgeons in Ireland, Dublin, Ireland

  ⨯
• Beatrice L. Colon,

  Affiliation Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States of America

  ⨯
• Daisy D. Colón-López,

  Affiliation Department of Biochemistry and Molecular Biology and Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, Untied States of America

  ⨯
• Yolanda Corbett,

  Affiliation Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milano, Italy

  ⨯
• Gregory J. Crowther,

  Affiliation Departments of Medicine, Microbiology, and Global Health, Center for Emerging and Re-emerging Infectious Diseases (CERID) University of Washington, Seattle, Washington, United States of America

  ⨯
• Noemi Cowan,

  Affiliations Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland

  ⨯
• Sarah D’Alessandro,

  Affiliation Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milano, Italy

  ⨯
• Na Le Dang,

  Affiliation Department of Pathology and Immunology, Washington University in St Louis, St. Louis, Missouri, United States of America

  ⨯
• Michael Delves,

  Affiliation Department of Life Sciences, Imperial College London, London, England, United Kingdom

  ⨯
• Joseph L. DeRisi,

  Affiliation Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of California, San Francisco, California, United States of America

  http://orcid.org/0000-0002-4611-9205

  ⨯
• Alan Y. Du,

  Affiliation Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California, United States of America

  ⨯
• Sandra Duffy,

  Affiliation Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia

  ⨯
• Shimaa Abd El-Salam El-Sayed,

  Affiliations National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan, Department of Biochemistry and Chemistry of nutrition, Mansoura University, Mansoura City, Egypt

  ⨯
• Michael T. Ferdig,

  Affiliation Eck Institute for Global Health, Department of Biological Sciences, University of Notre Dame, Notre Dame Indiana, United States of America

  ⨯
• José A. Fernández Robledo,

  Affiliation Bigelow Laboratory for Ocean Sciences, East Boothbay, Maine, United States of America

  ⨯
• David A. Fidock,

  Affiliation Department of Microbiology & Immunology and Division of Infectious Diseases, Department of Medicine, Columbia University Medical Center, New York, New York, United States of America

  ⨯
• Isabelle Florent,

  Affiliation Museum of National History, Sorbonne Universities, Paris, France

  ⨯
• Patrick V. T. Fokou,

  Affiliation Department of Biochemistry, University of Yaoundé, Yaoundé, Cameroon

  ⨯
• Ani Galstian,

  Affiliation Broad Institute, Cambridge, Massachusetts, United States of America

  ⨯
• Francisco Javier Gamo,

  Affiliation Biochemistry and Parasitology Department, Malaria DPU, Diseases of the Developing World (DDW), GlaxoSmithKline R&D, Tres Cantos, Madrid, Spain

  ⨯
• Suzanne Gokool,

  Affiliation Tropical Parasitic Diseases Unit, Northwick Park Institute for Medical Research, Harrow, Middlesex, England, United Kingdom

  http://orcid.org/0000-0002-8451-7044

  ⨯
• Ben Gold,

  Affiliation Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America

  ⨯
• Todd Golub,

  Affiliation Broad Institute, Cambridge, Massachusetts, United States of America

  ⨯
• Gregory M. Goldgof,

  Affiliation Medical Scientist Training Program, University of California, San Diego, San Diego, California, United States of America

  ⨯
• Rajarshi Guha,

  Affiliation National Center of Advancing Translational Sciences, NIH, Bethesda, Maryland, United States of America

  ⨯
• W. Armand Guiguemde,

  Affiliation Department of Chemical Biology & Therapeutics, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

  ⨯
• Nil Gural,

  Affiliation Health Sciences and Technology/Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

  ⨯
• R. Kiplin Guy,

  Affiliation Department of Chemical Biology & Therapeutics, St. Jude Children’s Research Hospital, Memphis, Tennessee, United States of America

  ⨯
• Michael A. E. Hansen,

  Affiliation Institut Pasteur Korea, Pangyo Techno-Valley, Gyeonggi Province, Korea

  ⨯
• Kirsten K. Hanson,

  Affiliations Dept. of Biology and South Texas Center for Emerging Infectious Diseases, University of Texas, San Antonio, San Antonio, Texas, United States of America, Instituto de Medicina Molecular, Lisboa, Portugal

  ⨯
• Andrew Hemphill,

  Affiliation Institute of Parasitology, University of Berne, Bern, Switzerland

  ⨯
• Rob Hooft van Huijsduijnen,

  Affiliation Medicines for Malaria Venture, Geneva, Switzerland

  ⨯
• Takaaki Horii,

  Affiliation Global Health Research Section, hhc Data Creation Center, Eisai Co., Ltd, Tsukuba-shi, Ibaraki, Japan

  ⨯
• Paul Horrocks,

  Affiliation Institute for Science and Technology in Medicine, Keele University, Keele, Staffordshire, United Kingdom

  ⨯
• Tyler B. Hughes,

  Affiliation Department of Pathology and Immunology, Washington University in St Louis, St. Louis, Missouri, United States of America

  ⨯
• Christopher Huston,

  Affiliation Department of Medicine, College of Medicine, University of Vermont, Burlington, Vermont, United States of America

  ⨯
• Ikuo Igarashi,

  Affiliation National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan

  ⨯
• Katrin Ingram-Sieber,

  Affiliations Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland

  ⨯
• Maurice A. Itoe,

  Affiliation Instituto de Medicina Molecular, Lisboa, Portugal

  ⨯
• Ajit Jadhav,

  Affiliation National Center of Advancing Translational Sciences, NIH, Bethesda, Maryland, United States of America

  ⨯
• Amornrat Naranuntarat Jensen,

  Affiliation Department of Pathobiology, Faculty of Science, Mahidol University, Bangkok Thailand

  ⨯
• Laran T. Jensen,

  Affiliation Department of Biochemistry, Mahidol University, Bangkok, Thailand

  ⨯
• Rays H. Y. Jiang,

  Affiliation Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida, United States of America

  ⨯
• Annette Kaiser,

  Affiliation Medical Research Centre, Institute for Pharmacogenetics, Essen, Germany

  ⨯
• Jennifer Keiser,

  Affiliations Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland

  ⨯
• Thomas Ketas,

  Affiliation Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America

  ⨯
• Sebastien Kicka,

  Affiliation Department of Biochemistry, University of Geneva, Geneva, Switzerland

  ⨯
• Sunyoung Kim,

  Affiliation Department of Biochemistry and Molecular Biology, LSU Health Sciences Center, New Orleans, Louisiana, United States of America

  ⨯
• Kiaran Kirk,

  Affiliation Research School of Biology, Australian National University, Canberra, Australian Capital Territory, Australia

  ⨯
• Vidya P. Kumar,

  Affiliation Internal Medicine, Yale University, New Haven, Connecticut, United States of America

  ⨯
• Dennis E. Kyle,

  Affiliation Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida, United States of America

  ⨯
• Maria Jose Lafuente,

  Affiliation Biochemistry and Parasitology Department, Malaria DPU, Diseases of the Developing World (DDW), GlaxoSmithKline R&D, Tres Cantos, Madrid, Spain

  ⨯
• Scott Landfear,

  Affiliation Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon, United States of America

  ⨯
• Nathan Lee,

  Affiliation Medicines for Malaria Venture, Geneva, Switzerland

  ⨯
• Sukjun Lee,

  Affiliation Institut Pasteur Korea, Pangyo Techno-Valley, Gyeonggi Province, Korea

  ⨯
• Adele M. Lehane,

  Affiliation Research School of Biology, Australian National University, Canberra, Australian Capital Territory, Australia

  ⨯
• Fengwu Li,

  Affiliation Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon, United States of America

  ⨯
• David Little,

  Affiliation Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America

  ⨯
• Liqiong Liu,

  Affiliation Department of Biochemistry and Molecular Biology, LSU Health Sciences Center, New Orleans, Louisiana, United States of America

  ⨯
• Manuel Llinás,

  Affiliation Department of Biochemistry and Molecular Biology and Huck Center for Malaria Research, Pennsylvania State University, University Park, Pennsylvania, United States of America

  ⨯
• Maria I. Loza,

  Affiliation CIMUS Research Centre, University of Santiago de Compostela, Santiago de Compostela, A Coruña, Spain

  ⨯
• Aristea Lubar,

  Affiliation Department of Medicine, University of California San Diego, San Diego, California, United States of America

  ⨯
• Leonardo Lucantoni,

  Affiliation Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia

  ⨯
• Isabelle Lucet,

  Affiliation Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia

  ⨯
• Louis Maes,

  Affiliation University of Antwerp, Department of Biomedical Sciences, Antwerp, Belgium

  ⨯
• Dalu Mancama,

  Affiliation Biosciences Unit, Council for Scientific and Industrial Research, Pretoria, South Africa

  ⨯
• Nuha R. Mansour,

  Affiliation Department of Immunology & Infection, London School of Hygiene and Tropical Medicine, London, England, United Kingdom

  ⨯
• Sandra March,

  Affiliation Health Sciences and Technology/Institute for Medical Engineering and Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

  ⨯
• Sheena McGowan,

  Affiliation Department of Microbiology, Monash University, Clayton, Australia

  ⨯
• Iset Medina Vera,

  Affiliation Instituto de Medicina Molecular, Lisboa, Portugal

  ⨯
• Stephan Meister,

  Affiliation Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California, United States of America

  ⨯
• Luke Mercer,

  Affiliation SCYNEXIS, Inc., Durham, North Carolina, United States of America

  ⨯
• Jordi Mestres,

  Affiliation Chemotargets S.L. and Research Group on Systems Pharmacology, Research Program on Biomedical Informatics (GRIB), IMIM Hospital del Mar Institute of Medical Research and University Pompeu Fabra, Barcelona, Catalonia, Spain

  ⨯
• Alvine N. Mfopa,

  Affiliation Department of Biochemistry, University of Yaoundé, Yaoundé, Cameroon

  ⨯
• Raj N. Misra,

  Affiliation Division of Cancer Therapeutics and Diagnosis, Drug Synthesis and Chemistry Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America

  ⨯
• Seunghyun Moon,

  Affiliation Institut Pasteur Korea, Pangyo Techno-Valley, Gyeonggi Province, Korea

  ⨯
• John P. Moore,

  Affiliation Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America

  ⨯
• Francielly Morais Rodrigues da Costa,

  Affiliation Graduate Program in Bioinformatics, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

  ⨯
• Joachim Müller,

  Affiliation Institute of Parasitology, University of Berne, Bern, Switzerland

  ⨯
• Arantza Muriana,

  Affiliation BBD BioPhenix SL–BIOBIDE, Donostia, Gipuzkoa, Spain

  ⨯
• Stephen Nakazawa Hewitt,

  Affiliation Departments of Medicine, Microbiology, and Global Health, Center for Emerging and Re-emerging Infectious Diseases (CERID) University of Washington, Seattle, Washington, United States of America

  ⨯
• Bakela Nare,

  Affiliation SCYNEXIS, Inc., Durham, North Carolina, United States of America

  ⨯
• Carl Nathan,

  Affiliation Department of Microbiology and Immunology, Weill Cornell Medical College, New York, New York, United States of America

  ⨯
• Nathalie Narraidoo,

  Affiliation School of Life Sciences, University of Nottingham, Nottingham, Nottinghamshire, England, United Kingdom

  ⨯
• Sujeevi Nawaratna,

  Affiliations Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia, QIMR Berghofer Medical Research Institute Herston, Brisbane, Australia

  ⨯
• Kayode K. Ojo,

  Affiliation Departments of Medicine, Microbiology, and Global Health, Center for Emerging and Re-emerging Infectious Diseases (CERID) University of Washington, Seattle, Washington, United States of America

  ⨯
• Diana Ortiz,

  Affiliation Department of Molecular Microbiology & Immunology, Oregon Health & Science University, Portland, Oregon, United States of America

  ⨯
• Gordana Panic,

  Affiliations Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Basel, Switzerland, University of Basel, Basel, Switzerland

  ⨯
• George Papadatos,

  Affiliation ChEMBL group, European Molecular Biology Laboratory—European Bioinformatics Institute (EMBL-EBI), Hinxton, Cambridgeshire, United Kingdom

  ⨯
• Silvia Parapini,

  Affiliation Department of Pharmacological and Biomolecular Sciences, Università degli Studi di Milano, Milano, Italy

  ⨯
• Kailash Patra,

  Affiliation Department of Medicine, University of California San Diego, San Diego, California, United States of America

  ⨯
• Ngoc Pham,

  Affiliation Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia

  ⨯
• Sarah Prats,

  Affiliation Biochemistry and Parasitology Department, Malaria DPU, Diseases of the Developing World (DDW), GlaxoSmithKline R&D, Tres Cantos, Madrid, Spain

  ⨯
• David M. Plouffe,

  Affiliation Genomics Institute of the Novartis Research Foundation, San Diego, California, United States of America

  ⨯
• Sally-Ann Poulsen,

  Affiliation Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia

  ⨯
• Anupam Pradhan,

  Affiliation Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida, United States of America

  ⨯
• Celia Quevedo,

  Affiliation BBD BioPhenix SL–BIOBIDE, Donostia, Gipuzkoa, Spain

  ⨯
• Ronald J. Quinn,

  Affiliation Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia

  ⨯
• Christopher A. Rice,

  Affiliation Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida, United States of America

  ⨯
• Mohamed Abdo Rizk,

  Affiliations National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan, Department of Internal Medicine and Infectious Diseases, Faculty of Veterinary Medicine, Mansoura University, Mansoura City, Egypt

  ⨯
• Andrea Ruecker,

  Affiliation Department of Life Sciences, Imperial College London, London, England, United Kingdom

  ⨯
• Robert St. Onge,

  Affiliation Department of Biochemistry and Stanford Genome Technology Center, Stanford University, Palo Alto, Calilfornia, United States of America

  ⨯
• Rafaela Salgado Ferreira,

  Affiliation Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

  ⨯
• Jasmeet Samra,

  Affiliation Department of Biochemistry and Molecular Biology and Huck Center for Malaria Research, Pennsylvania State University, University Park, Pennsylvania, United States of America

  ⨯
• Natalie G. Robinett,

  Affiliations Department of Biochemistry and Molecular Biology and Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, Untied States of America, Laboratoire de Chimie Moléculaire, CNRS,—UMR 7509, COB-IRJBD, Mulhouse Cedex, France

  ⨯
• Ulrich Schlecht,

  Affiliation Department of Biochemistry and Stanford Genome Technology Center, Stanford University, Palo Alto, Calilfornia, United States of America

  ⨯
• Marjorie Schmitt,

  Affiliation Laboratoire de Chimie Moléculaire, CNRS,—UMR 7509, COB-IRJBD, Mulhouse Cedex, France

  ⨯
• Filipe Silva Villela,

  Affiliation Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

  ⨯
• Francesco Silvestrini,

  Affiliation Dipartimento Malattie Infettive, Parassitarie ed Immunomediate Istituto Superiore di Sanità, Roma, Italia

  ⨯
• Robert Sinden,

  Affiliation The Jenner Institute, University of Oxford, Oxford, England, United Kingdom

  ⨯
• Dennis A. Smith,

  Affiliation Department of Chemistry, University of Capetown, Capetown, South Africa

  ⨯
• Thierry Soldati,

  Affiliation Department of Biochemistry, University of Geneva, Geneva, Switzerland

  ⨯
• Andreas Spitzmüller,

  Affiliation Chemotargets S.L. and Research Group on Systems Pharmacology, Research Program on Biomedical Informatics (GRIB), IMIM Hospital del Mar Institute of Medical Research and University Pompeu Fabra, Barcelona, Catalonia, Spain

  ⨯
• Serge Maximilian Stamm,

  Affiliation Department of Biochemistry and Molecular Biology and Johns Hopkins Malaria Research Institute, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, Untied States of America

  ⨯
• David J. Sullivan,

  Affiliation H. Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health, Baltimore, Maryland, United States of America

  ⨯
• William Sullivan,

  Affiliation Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, California, United States of America

  ⨯
• Sundari Suresh,

  Affiliation Departamento de Bioquímica e Imunologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

  ⨯
• Brian M. Suzuki,

  Affiliation Center for Discovery and Innovation in Parasitic Diseases, Department of Pathology, University of California San Francisco, San Francisco, California, United States of America

  ⨯
• Yo Suzuki,

  Affiliation Department of Synthetic Biology and Bioenergy, J. Craig Venter Institute, La Jolla, California, United States of America

  ⨯
• S. Joshua Swamidass,

  Affiliation Department of Life Sciences, Imperial College London, London, England, United Kingdom

  ⨯
• Donatella Taramelli,

  Affiliation Department of Pathology and Immunology, Washington University in St Louis, St. Louis, Missouri, United States of America

  ⨯
• Lauve R. Y. Tchokouaha,

  Affiliation Department of Biochemistry, University of Yaoundé, Yaoundé, Cameroon

  ⨯
• Anjo Theron,

  Affiliation Biosciences Unit, Council for Scientific and Industrial Research, Pretoria, South Africa

  ⨯
• David Thomas,

  Affiliation Broad Institute, Cambridge, Massachusetts, United States of America

  ⨯
• Kathryn F. Tonissen,

  Affiliations Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia, School of Natural Sciences, Griffith University, Nathan, Queensland, Australia

  ⨯
• Simon Townson,

  Affiliation Tropical Parasitic Diseases Unit, Northwick Park Institute for Medical Research, Harrow, Middlesex, England, United Kingdom

  ⨯
• Abhai K. Tripathi,

  Affiliation H. Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins School of Public Health, Baltimore, Maryland, United States of America

  ⨯
• Valentin Trofimov,

  Affiliation Department of Biochemistry, University of Geneva, Geneva, Switzerland

  ⨯
• Kenneth O. Udenze,

  Affiliation Center for Global Health and Infectious Diseases Research, Department of Global Health, University of South Florida, Tampa, Florida, United States of America

  ⨯
• Imran Ullah,

  Affiliation Institute for Science and Technology in Medicine, Keele University, Keele, Staffordshire, United Kingdom

  ⨯
• Cindy Vallieres,

  Affiliation School of Life Sciences, University of Nottingham, Nottingham, Nottinghamshire, England, United Kingdom

  ⨯
• Edgar Vigil,

  Affiliation Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California, United States of America

  ⨯
• Joseph M. Vinetz,

  Affiliation Department of Medicine, University of California San Diego, San Diego, California, United States of America

  ⨯
• Phat Voong Vinh,

  Affiliation Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme, The Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam

  ⨯
• Hoan Vu,

  Affiliation Eskitis Institute for Drug Discovery, Griffith University, Nathan, QLD, Australia

  ⨯
• Nao-aki Watanabe,

  Affiliation Global Health Research Section, hhc Data Creation Center, Eisai Co., Ltd, Tsukuba-shi, Ibaraki, Japan

  ⨯
• Kate Weatherby,

  Affiliation School of Life and Environmental Sciences, University of Sydney, Darlington New South Wales, Australia

  ⨯
• Pamela M. White,

  Affiliation Molecular, Cell and Developmental Biology, University of California, Santa Cruz, Santa Cruz, California, United States of America

  ⨯
• Andrew F. Wilks,

  Affiliations Hudson Institute of Medical Research; Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia, SYNthesis Research, Parkville, Victoria, Australia

  ⨯
• Elizabeth A. Winzeler,

  Affiliation Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California, United States of America

  ⨯
• Edward Wojcik,

  Affiliation Department of Biochemistry and Molecular Biology, LSU Health Sciences Center, New Orleans, Louisiana, United States of America

  ⨯
• Melanie Wree,

  Affiliation Division of Pharmacology and Drug Discovery, Department of Pediatrics, School of Medicine University of California San Diego, La Jolla, California, United States of America

  ⨯
• Wesley Wu,

  Affiliation Howard Hughes Medical Institute, Department of Biochemistry and Biophysics, University of California, San Francisco, California, United States of America

  ⨯
• Naoaki Yokoyama,

  Affiliation National Research Center for Protozoan Diseases, Obihiro University of Agriculture and Veterinary Medicine, Obihiro, Hokkaido, Japan

  ⨯
• Paul H. A. Zollo,

  Affiliation Department of Biochemistry, University of Yaoundé, Yaoundé, Cameroon

  ⨯
• Nada Abla,

  Affiliation Medicines for Malaria Venture, Geneva, Switzerland

  ⨯
• Benjamin Blasco,

  Affiliation Medicines for Malaria Venture, Geneva, Switzerland

  ⨯
• Jeremy Burrows,

  Affiliation Medicines for Malaria Venture, Geneva, Switzerland

  ⨯
• Benoît Laleu,

  Affiliation Medicines for Malaria Venture, Geneva, Switzerland

  ⨯
• Didier Leroy,

  Affiliation Medicines for Malaria Venture, Geneva, Switzerland

  ⨯
• Thomas Spangenberg,

  Current address: Global Health, Merck, Coinsins, Switzerland

  Affiliation Medicines for Malaria Venture, Geneva, Switzerland

  ⨯
• Timothy Wells,

  Affiliation Medicines for Malaria Venture, Geneva, Switzerland

  ⨯
•  [ ... ],
• Paul A. Willis

  Affiliation Medicines for Malaria Venture, Geneva, Switzerland

  ⨯
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