Epigenetic Switch Driven by DNA Inversions Dictates Phase Variation in Streptococcus pneumoniae

• Jing Li ,

  Contributed equally to this work with: Jing Li, Jing-Wen Li, Zhixing Feng

  Affiliation Center for Infectious Disease Research, School of Medicine, Tsinghua University, Beijing, China

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• Jing-Wen Li ,

  Contributed equally to this work with: Jing Li, Jing-Wen Li, Zhixing Feng

  Affiliation Center for Infectious Disease Research, School of Medicine, Tsinghua University, Beijing, China

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• Zhixing Feng ,

  Contributed equally to this work with: Jing Li, Jing-Wen Li, Zhixing Feng

  Affiliation Department of Genetics and Genomic Sciences, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

  http://orcid.org/0000-0003-0308-8549

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• Juanjuan Wang,

  Affiliation Center for Infectious Disease Research, School of Medicine, Tsinghua University, Beijing, China

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• Haoran An,

  Affiliation Center for Infectious Disease Research, School of Medicine, Tsinghua University, Beijing, China

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• Yanni Liu,

  Affiliation Center for Infectious Disease Research, School of Medicine, Tsinghua University, Beijing, China

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• Yang Wang,

  Affiliation Center for Infectious Disease Research, School of Medicine, Tsinghua University, Beijing, China

  http://orcid.org/0000-0002-5117-7055

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• Kailing Wang,

  Affiliation Center for Infectious Disease Research, School of Medicine, Tsinghua University, Beijing, China

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• Xuegong Zhang,

  Affiliation MOE Key Laboratory of Bioinformatics, Bioinformatics Division, TNLIST and Department of Automation, Tsinghua University, Beijing, China

  http://orcid.org/0000-0002-9684-5643

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• Zhun Miao,

  Affiliation MOE Key Laboratory of Bioinformatics, Bioinformatics Division, TNLIST and Department of Automation, Tsinghua University, Beijing, China

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• Wenbo Liang,

  Affiliation College of Veterinary Medicine, Gansu Agricultural University, Lanzhou, Gansu, China

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• Robert Sebra,

  Affiliation Department of Genetics and Genomic Sciences, Icahn Institute of Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America

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• Guilin Wang,

  Affiliation W. M. Keck Foundation Biotechnology Resource Laboratory, Yale University, New Haven, Connecticut, United States of America

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• Wen-Ching Wang,

  Affiliation Biomedical Science and Engineering Center, Institute of Molecular and Cellular Biology, National Tsing Hua University, Hsinchu, Taiwan

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• Jing-Ren Zhang

  * E-mail: zhanglab@tsinghua.edu.cn

  Affiliations Center for Infectious Disease Research, School of Medicine, Tsinghua University, Beijing, China, Collaborative Innovation Center for Biotherapy, State Key Laboratory of Biotherapy and Center, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China

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