CD4 T Cell-Derived IFN-γ Plays a Minimal Role in Control of Pulmonary Mycobacterium tuberculosis Infection and Must Be Actively Repressed by PD-1 to Prevent Lethal Disease

• Shunsuke Sakai,

  Affiliation T lymphocyte Biology Unit, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

  ⨯
• Keith D. Kauffman,

  Affiliation T lymphocyte Biology Unit, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

  ⨯
• Michelle A. Sallin,

  Affiliation T lymphocyte Biology Unit, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

  ⨯
• Arlene H. Sharpe,

  Affiliation Department of Microbiology and Immunobiology, and Evergrande Center for Immunological Diseases, Harvard Medical School and Brigham and Women’s Hospital, Boston, Massachusetts, United States of America

  ⨯
• Howard A. Young,

  Affiliation Cancer and Inflammation Program, National Cancer Institute, Frederick, Maryland, United States of America

  ⨯
• Vitaly V. Ganusov,

  Affiliation Department of Microbiology, University of Tennessee, Knoxville, Tennessee, United States of America

  ⨯
• Daniel L. Barber

  * E-mail: barberd@niaid.nih.gov

  Affiliation T lymphocyte Biology Unit, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, United States of America

  ⨯