Chimeric Mice with Competent Hematopoietic Immunity Reproduce Key Features of Severe Lassa Fever

Lisa Oestereich; Anja Lüdtke; Paula Ruibal; Elisa Pallasch; Romy Kerber; Toni Rieger; Stephanie Wurr; Sabrina Bockholt; José V. Pérez-Girón; Susanne Krasemann; Stephan Günther; César Muñoz-Fontela

doi:10.1371/journal.ppat.1005656

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Open Access

Peer-reviewed

Research Article

Chimeric Mice with Competent Hematopoietic Immunity Reproduce Key Features of Severe Lassa Fever

Lisa Oestereich,

Affiliations Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany, German Center for Infection Research (DZIF), Partner Site Hamburg, Hamburg, Germany
⨯
Anja Lüdtke,

Affiliations Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany, German Center for Infection Research (DZIF), Partner Site Hamburg, Hamburg, Germany, Heinrich Pette Institute, Leibniz Institute For Experimental Virology, Hamburg, Germany
⨯
Paula Ruibal,

Affiliations Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany, German Center for Infection Research (DZIF), Partner Site Hamburg, Hamburg, Germany, Heinrich Pette Institute, Leibniz Institute For Experimental Virology, Hamburg, Germany
⨯
Elisa Pallasch,

Affiliations Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany, German Center for Infection Research (DZIF), Partner Site Hamburg, Hamburg, Germany
⨯
Romy Kerber,

Affiliations Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany, German Center for Infection Research (DZIF), Partner Site Hamburg, Hamburg, Germany
⨯
Toni Rieger,

Affiliations Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany, German Center for Infection Research (DZIF), Partner Site Hamburg, Hamburg, Germany
⨯
Stephanie Wurr,

Affiliations Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany, German Center for Infection Research (DZIF), Partner Site Hamburg, Hamburg, Germany
⨯
Sabrina Bockholt,

Affiliations Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany, German Center for Infection Research (DZIF), Partner Site Hamburg, Hamburg, Germany
⨯
José V. Pérez-Girón †,

† Deceased.

Affiliation Heinrich Pette Institute, Leibniz Institute For Experimental Virology, Hamburg, Germany
⨯
Susanne Krasemann,

Affiliation Institute for Neuropathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
⨯
Stephan Günther ,

Contributed equally to this work with: Stephan Günther, César Muñoz-Fontela

Affiliations Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany, German Center for Infection Research (DZIF), Partner Site Hamburg, Hamburg, Germany
⨯
César Muñoz-Fontela

Contributed equally to this work with: Stephan Günther, César Muñoz-Fontela

* E-mail: cesar.munoz-fontela@hpi.uni-hamburg.de

Affiliations Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany, German Center for Infection Research (DZIF), Partner Site Hamburg, Hamburg, Germany, Heinrich Pette Institute, Leibniz Institute For Experimental Virology, Hamburg, Germany
⨯

Chimeric Mice with Competent Hematopoietic Immunity Reproduce Key Features of Severe Lassa Fever

Lisa Oestereich,
Anja Lüdtke,
Paula Ruibal,
Elisa Pallasch,
Romy Kerber,
Toni Rieger,
Stephanie Wurr,
Sabrina Bockholt,
José V. Pérez-Girón,
Susanne Krasemann

Published: May 18, 2016
https://doi.org/10.1371/journal.ppat.1005656

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