Virus Infections Incite Pain Hypersensitivity by Inducing Indoleamine 2,3 Dioxygenase

Lei Huang; Rong Ou; Guilherme Rabelo de Souza; Thiago M. Cunha; Henrique Lemos; Eslam Mohamed; Lingqian Li; Gabriela Pacholczyk; Janice Randall; David H. Munn; Andrew L. Mellor

doi:10.1371/journal.ppat.1005615

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Open Access

Peer-reviewed

Research Article

Virus Infections Incite Pain Hypersensitivity by Inducing Indoleamine 2,3 Dioxygenase

Lei Huang ,

* E-mail: lhuang@augusta.edu (LH); amellor@augusta.edu (ALM)

Affiliation Cancer Immunology, Inflammation and Tolerance Program, Cancer Center, Augusta University, Augusta, Georgia, United States of America
⨯
Rong Ou,

Current address: Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Framlington Place, Newcastle-upon-Tyne, NE2 4HH, UK.

Affiliation Cancer Immunology, Inflammation and Tolerance Program, Cancer Center, Augusta University, Augusta, Georgia, United States of America
⨯
Guilherme Rabelo de Souza,

Affiliation Department of Pharmacology, Ribeirao Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
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Thiago M. Cunha,

Affiliation Department of Pharmacology, Ribeirao Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil
⨯
Henrique Lemos,

Current address: Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Framlington Place, Newcastle-upon-Tyne, NE2 4HH, UK.

Affiliation Cancer Immunology, Inflammation and Tolerance Program, Cancer Center, Augusta University, Augusta, Georgia, United States of America
⨯
Eslam Mohamed,

Affiliation Cancer Immunology, Inflammation and Tolerance Program, Cancer Center, Augusta University, Augusta, Georgia, United States of America
⨯
Lingqian Li,

Affiliation Cancer Immunology, Inflammation and Tolerance Program, Cancer Center, Augusta University, Augusta, Georgia, United States of America
⨯
Gabriela Pacholczyk,

Affiliation Cancer Immunology, Inflammation and Tolerance Program, Cancer Center, Augusta University, Augusta, Georgia, United States of America
⨯
Janice Randall,

Affiliation Cancer Immunology, Inflammation and Tolerance Program, Cancer Center, Augusta University, Augusta, Georgia, United States of America
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David H. Munn,

Affiliation Cancer Immunology, Inflammation and Tolerance Program, Cancer Center, Augusta University, Augusta, Georgia, United States of America
⨯
Andrew L. Mellor

* E-mail: lhuang@augusta.edu (LH); amellor@augusta.edu (ALM)

Current address: Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Framlington Place, Newcastle-upon-Tyne, NE2 4HH, UK.

Affiliation Cancer Immunology, Inflammation and Tolerance Program, Cancer Center, Augusta University, Augusta, Georgia, United States of America
⨯

Virus Infections Incite Pain Hypersensitivity by Inducing Indoleamine 2,3 Dioxygenase

Lei Huang,
Rong Ou,
Guilherme Rabelo de Souza,
Thiago M. Cunha,
Henrique Lemos,
Eslam Mohamed,
Lingqian Li,
Gabriela Pacholczyk,
Janice Randall,
David H. Munn

Published: May 11, 2016
https://doi.org/10.1371/journal.ppat.1005615

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