Endosomal MR1 Trafficking Plays a Key Role in Presentation of Mycobacterium tuberculosis Ligands to MAIT Cells

Melanie J. Harriff; Elham Karamooz; Ansen Burr; Wilmon F. Grant; Elizabeth T. Canfield; Michelle L. Sorensen; Luis F. Moita; David M. Lewinsohn

doi:10.1371/journal.ppat.1005524

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Peer-reviewed

Research Article

Endosomal MR1 Trafficking Plays a Key Role in Presentation of Mycobacterium tuberculosis Ligands to MAIT Cells

Melanie J. Harriff ,

Contributed equally to this work with: Melanie J. Harriff, Elham Karamooz

* E-mail: harriffm@ohsu.edu (MJH); lewinsod@ohsu.edu (DML)

Affiliations Portland VA Medical Center, Portland, Oregon, United States of America, Pulmonary & Critical Care Medicine, Oregon Health & Science University, Portland, Oregon, United States of America
⨯
Elham Karamooz ,

Contributed equally to this work with: Melanie J. Harriff, Elham Karamooz

Affiliations Portland VA Medical Center, Portland, Oregon, United States of America, Pulmonary & Critical Care Medicine, Oregon Health & Science University, Portland, Oregon, United States of America
⨯
Ansen Burr,

Affiliation Portland VA Medical Center, Portland, Oregon, United States of America
⨯
Wilmon F. Grant,

Affiliation Pulmonary & Critical Care Medicine, Oregon Health & Science University, Portland, Oregon, United States of America
⨯
Elizabeth T. Canfield,

Affiliation Pulmonary & Critical Care Medicine, Oregon Health & Science University, Portland, Oregon, United States of America
⨯
Michelle L. Sorensen,

Affiliation Portland VA Medical Center, Portland, Oregon, United States of America
⨯
Luis F. Moita,

Affiliation Instituto Gulbenkian de Ciência, Oeiras, Portugal
⨯
David M. Lewinsohn

* E-mail: harriffm@ohsu.edu (MJH); lewinsod@ohsu.edu (DML)

Affiliations Portland VA Medical Center, Portland, Oregon, United States of America, Pulmonary & Critical Care Medicine, Oregon Health & Science University, Portland, Oregon, United States of America, Molecular Microbiology and Immunology, Oregon Health & Science University, Portland, Oregon, United States of America
⨯

Endosomal MR1 Trafficking Plays a Key Role in Presentation of Mycobacterium tuberculosis Ligands to MAIT Cells

Melanie J. Harriff,
Elham Karamooz,
Ansen Burr,
Wilmon F. Grant,
Elizabeth T. Canfield,
Michelle L. Sorensen,
Luis F. Moita,
David M. Lewinsohn

Published: March 31, 2016
https://doi.org/10.1371/journal.ppat.1005524

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