Quantitative Trait Locus Based Virulence Determinant Mapping of the HSV-1 Genome in Murine Ocular Infection: Genes Involved in Viral Regulatory and Innate Immune Networks Contribute to Virulence

• Aaron W. Kolb ,

  Contributed equally to this work with: Aaron W. Kolb, Kyubin Lee

  Affiliation Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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• Kyubin Lee ,

  Contributed equally to this work with: Aaron W. Kolb, Kyubin Lee

  Affiliations Department of Computer Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Department of Biostatistics and Medical Informatics, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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• Inna Larsen,

  Affiliation Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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• Mark Craven,

  Affiliations Department of Biostatistics and Medical Informatics, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Department of Computer Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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• Curtis R. Brandt

  * E-mail: crbrandt@wisc.edu

  Affiliations Department of Ophthalmology and Visual Sciences, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, Department of Medical Microbiology and Immunology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, United States of America, McPherson Eye Research Institute, University of Wisconsin-Madison, Madison, Wisconsin, United States of America

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