TIM3 Mediates T Cell Exhaustion during Mycobacterium tuberculosis Infection

Pushpa Jayaraman; Miye K. Jacques; Chen Zhu; Katherine M. Steblenko; Britni L. Stowell; Asaf Madi; Ana C. Anderson; Vijay K. Kuchroo; Samuel M. Behar

doi:10.1371/journal.ppat.1005490

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Open Access

Peer-reviewed

Research Article

TIM3 Mediates T Cell Exhaustion during Mycobacterium tuberculosis Infection

Pushpa Jayaraman,

Affiliation Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Miye K. Jacques,

Affiliation Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Chen Zhu,

Affiliation Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Katherine M. Steblenko,

Affiliation Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Britni L. Stowell,

Affiliation Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Asaf Madi,

Affiliation Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Ana C. Anderson,

Affiliation Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Vijay K. Kuchroo,

Affiliation Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, United States of America
⨯
Samuel M. Behar

* E-mail: samuel.behar@umassmed.edu

Affiliation Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯

TIM3 Mediates T Cell Exhaustion during Mycobacterium tuberculosis Infection

Pushpa Jayaraman,
Miye K. Jacques,
Chen Zhu,
Katherine M. Steblenko,
Britni L. Stowell,
Asaf Madi,
Ana C. Anderson,
Vijay K. Kuchroo,
Samuel M. Behar

Published: March 11, 2016
https://doi.org/10.1371/journal.ppat.1005490

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