Loss of Function of Intestinal IL-17 and IL-22 Producing Cells Contributes to Inflammation and Viral Persistence in SIV-Infected Rhesus Macaques

Emily S. Ryan; Luca Micci; Rémi Fromentin; Sara Paganini; Colleen S. McGary; Kirk Easley; Nicolas Chomont; Mirko Paiardini

doi:10.1371/journal.ppat.1005412

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Peer-reviewed

Research Article

Loss of Function of Intestinal IL-17 and IL-22 Producing Cells Contributes to Inflammation and Viral Persistence in SIV-Infected Rhesus Macaques

Emily S. Ryan ,

Contributed equally to this work with: Emily S. Ryan, Luca Micci

Affiliation Division of Microbiology & Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, United States of America
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Luca Micci ,

Contributed equally to this work with: Emily S. Ryan, Luca Micci

Affiliation Division of Microbiology & Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, United States of America
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Rémi Fromentin,

Affiliation Department of Microbiology, Infectiology and Immunology, Université de Montréal, Faculty of Medicine, and Centre de Recherche du CHUM, Montreal, Québec, Canada
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Sara Paganini,

Affiliation Division of Microbiology & Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, United States of America
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Colleen S. McGary,

Affiliation Division of Microbiology & Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, United States of America
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Kirk Easley,

Affiliation Department of Biostatistics & Bioinformatics, Rollins School of Public Health, Emory University, Atlanta, Georgia, United States of America
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Nicolas Chomont,

Affiliation Department of Microbiology, Infectiology and Immunology, Université de Montréal, Faculty of Medicine, and Centre de Recherche du CHUM, Montreal, Québec, Canada
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Mirko Paiardini

* E-mail: mirko.paiardini@emory.edu

Affiliations Division of Microbiology & Immunology, Yerkes National Primate Research Center, Emory University School of Medicine, Atlanta, Georgia, United States of America, Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia, United States of America
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Loss of Function of Intestinal IL-17 and IL-22 Producing Cells Contributes to Inflammation and Viral Persistence in SIV-Infected Rhesus Macaques

Emily S. Ryan,
Luca Micci,
Rémi Fromentin,
Sara Paganini,
Colleen S. McGary,
Kirk Easley,
Nicolas Chomont,
Mirko Paiardini

Published: February 1, 2016
https://doi.org/10.1371/journal.ppat.1005412

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