IFNs Modify the Proteome of Legionella-Containing Vacuoles and Restrict Infection Via IRG1-Derived Itaconic Acid

• Jan Naujoks,

  Affiliation Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité University Medicine Berlin, Berlin, Germany

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• Christoph Tabeling ,

  Contributed equally to this work with: Christoph Tabeling, Brian D. Dill, Christine Hoffmann, Andrew S. Brown

  Affiliation Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité University Medicine Berlin, Berlin, Germany

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• Brian D. Dill ,

  Contributed equally to this work with: Christoph Tabeling, Brian D. Dill, Christine Hoffmann, Andrew S. Brown

  Current address: Proteomics Resource Center, The Rockefeller University, New York, New York, United States of America

  Affiliation MRC Protein Phosphorylation Unit, University of Dundee, Dundee, United Kingdom

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• Christine Hoffmann ,

  Contributed equally to this work with: Christoph Tabeling, Brian D. Dill, Christine Hoffmann, Andrew S. Brown

  Affiliation Max-von-Pettenkofer Institute, Ludwig Maximilian University, Munich, Germany

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• Andrew S. Brown ,

  Contributed equally to this work with: Christoph Tabeling, Brian D. Dill, Christine Hoffmann, Andrew S. Brown

  Affiliation The Department of Biochemistry and Molecular Biology, The University of Melbourne, Melbourne, Australia

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• Mareike Kunze,

  Affiliation Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité University Medicine Berlin, Berlin, Germany

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• Stefan Kempa,

  Affiliation Integrative Metabolomics and Proteomics, Institute of Medical Systems Biology/Max-Delbrueck Center for Molecular Medicine, Berlin, Germany

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• Andrea Peter,

  Affiliation Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité University Medicine Berlin, Berlin, Germany

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• Hans-Joachim Mollenkopf,

  Affiliation Max Planck Institute for Infection Biology, Berlin, Germany

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• Anca Dorhoi,

  Affiliation Max Planck Institute for Infection Biology, Berlin, Germany

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• Olivia Kershaw,

  Affiliation Department of Veterinary Pathology, Free University Berlin, Berlin, Germany

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• Achim D. Gruber,

  Affiliation Department of Veterinary Pathology, Free University Berlin, Berlin, Germany

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• Leif E. Sander,

  Affiliation Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité University Medicine Berlin, Berlin, Germany

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• Martin Witzenrath,

  Affiliation Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité University Medicine Berlin, Berlin, Germany

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• Susanne Herold,

  Affiliation Medizinische Klinik II, University Giessen and Marburg Lung Center, Justus-Liebig-University Giessen, Giessen, Germany

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• Andreas Nerlich,

  Affiliation Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité University Medicine Berlin, Berlin, Germany

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• Andreas C. Hocke,

  Affiliation Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité University Medicine Berlin, Berlin, Germany

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• Ian van Driel,

  Affiliation The Department of Biochemistry and Molecular Biology, The University of Melbourne, Melbourne, Australia

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• Norbert Suttorp,

  Affiliation Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité University Medicine Berlin, Berlin, Germany

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• Sammy Bedoui ,

  ¶‡ These authors also contributed equally to this work.

  Affiliation The Department of Microbiology and Immunology, The University of Melbourne, Melbourne, Australia

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• Hubert Hilbi ,

  ¶‡ These authors also contributed equally to this work.

  Affiliations Max-von-Pettenkofer Institute, Ludwig Maximilian University, Munich, Germany, Institute of Medical Microbiology, University of Zurich, Zurich, Switzerland

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• Matthias Trost ,

  ¶‡ These authors also contributed equally to this work.

  Affiliation MRC Protein Phosphorylation Unit, University of Dundee, Dundee, United Kingdom

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•  [ ... ],
• Bastian Opitz

  * E-mail: bastian.opitz@charite.de

  Affiliation Department of Internal Medicine/Infectious Diseases and Pulmonary Medicine, Charité University Medicine Berlin, Berlin, Germany

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