TNF Drives Monocyte Dysfunction with Age and Results in Impaired Anti-pneumococcal Immunity

• Alicja Puchta ,

  Contributed equally to this work with: Alicja Puchta, Avee Naidoo

  Affiliations Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada, McMaster Immunology Research Centre, McMaster University, Hamilton, Canada, Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Canada

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• Avee Naidoo ,

  Contributed equally to this work with: Alicja Puchta, Avee Naidoo

  Affiliations Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada, McMaster Immunology Research Centre, McMaster University, Hamilton, Canada, Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Canada

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• Chris P. Verschoor,

  Affiliations Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada, McMaster Immunology Research Centre, McMaster University, Hamilton, Canada, Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Canada

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• Dessi Loukov,

  Affiliations Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada, McMaster Immunology Research Centre, McMaster University, Hamilton, Canada, Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Canada

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• Netusha Thevaranjan,

  Affiliations Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada, McMaster Immunology Research Centre, McMaster University, Hamilton, Canada, Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Canada

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• Talveer S. Mandur,

  Affiliations Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada, McMaster Immunology Research Centre, McMaster University, Hamilton, Canada

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• Phuong-son Nguyen,

  Affiliation Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, United States of America

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• Manel Jordana,

  Affiliations Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada, McMaster Immunology Research Centre, McMaster University, Hamilton, Canada

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• Mark Loeb,

  Affiliations Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Canada, Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Canada

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• Zhou Xing,

  Affiliations Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada, McMaster Immunology Research Centre, McMaster University, Hamilton, Canada, Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Canada

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• Lester Kobzik,

  Affiliation Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, United States of America

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• Maggie J. Larché,

  Affiliation Department of Medicine, McMaster University, Hamilton, Canada

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• Dawn M. E. Bowdish

  * E-mail: bowdish@mcmaster.ca

  Affiliations Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Canada, McMaster Immunology Research Centre, McMaster University, Hamilton, Canada, Michael G. DeGroote Institute for Infectious Disease Research, McMaster University, Hamilton, Canada

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