Structural Based Analyses of the JC Virus T-Antigen F258L Mutant Provides Evidence for DNA Dependent Conformational Changes in the C-Termini of Polyomavirus Origin Binding Domains

Open Access

Peer-reviewed

Research Article

Gretchen Meinke,

Affiliation Department of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, Massachusetts, United States of America
⨯
Paul J. Phelan,

Affiliation Department of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, Massachusetts, United States of America
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Jong Shin,

Affiliations Department of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, Massachusetts, United States of America, Sackler Institute of Graduate Biomedical Sciences, New York University School of Medicine, New York, New York, United States of America
⨯
David Gagnon,

Affiliations Institut de Recherches Cliniques de Montreal (IRCM), Montreal, Quebec, Canada, Department of Biochemistry and Molecular Medicine, Universite de Montreal, Montreal, Quebec, Canada
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Jacques Archambault,

Affiliations Institut de Recherches Cliniques de Montreal (IRCM), Montreal, Quebec, Canada, Department of Biochemistry and Molecular Medicine, Universite de Montreal, Montreal, Quebec, Canada
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Andrew Bohm,

Affiliation Department of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, Massachusetts, United States of America
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Peter A. Bullock

* E-mail: Peter.Bullock@tufts.edu

Affiliation Department of Developmental, Molecular and Chemical Biology, Tufts University School of Medicine, Boston, Massachusetts, United States of America
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