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Open Access
Peer-reviewed
Research Article
Bacterial Hypoxic Responses Revealed as Critical Determinants of the Host-Pathogen Outcome by TnSeq Analysis of Staphylococcus aureus Invasive Infection
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Aimee D. Wilde,
Affiliation Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
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Daniel J. Snyder,
Affiliation Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
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Nicole E. Putnam,
Affiliation Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
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Michael D. Valentino,
Current address: Exosome Diagnostics, Inc. Riverside Technology Center, Cambridge, Massachusetts, United States of America
Affiliation Departments of Ophthalmology and Microbiology and Immunology, Harvard Medical School, Boston, Massachusetts, United States of America
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Neal D. Hammer,
Affiliation Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
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Zachery R. Lonergan,
Affiliation Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
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Scott A. Hinger,
Affiliation Department of Biological Sciences, Vanderbilt University, Nashville, Tennessee, United States of America
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Esar E. Aysanoa,
Affiliation Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
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Catlyn Blanchard,
Affiliation Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America
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Paul M. Dunman,
Affiliation Department of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, United States of America
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Gregory A. Wasserman,
Current address: Department of Microbiology, Boston University School of Medicine, Boston, Massachusetts, United States of America
Affiliation Departments of Medicine and Microbiology, New York University School of Medicine, New York, New York, United States of America
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John Chen,
Current address: Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore
Affiliation Skirball Institute Program in Molecular Pathogenesis, Departments of Microbiology and Medicine, New York University Medical Center, New York, New York, United States of America
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Bo Shopsin,
Affiliation Departments of Medicine and Microbiology, New York University School of Medicine, New York, New York, United States of America
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Michael S. Gilmore,
Affiliation Departments of Ophthalmology and Microbiology and Immunology, Harvard Medical School, Boston, Massachusetts, United States of America
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Eric P. Skaar,
Affiliations Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Veterans Affairs Tennessee Valley Healthcare Services, Nashville, Tennessee, United States of America
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James E. Cassat
* E-mail: jim.cassat@vanderbilt.edu
Affiliations Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Department of Pediatrics, Division of Pediatric Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
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Bacterial Hypoxic Responses Revealed as Critical Determinants of the Host-Pathogen Outcome by TnSeq Analysis of Staphylococcus aureus Invasive Infection
- Aimee D. Wilde,
- Daniel J. Snyder,
- Nicole E. Putnam,
- Michael D. Valentino,
- Neal D. Hammer,
- Zachery R. Lonergan,
- Scott A. Hinger,
- Esar E. Aysanoa,
- Catlyn Blanchard,
- Paul M. Dunman
- Published: December 18, 2015
- https://doi.org/10.1371/journal.ppat.1005341