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Open Access
Peer-reviewed
Research Article
Crystal Structure of the Pre-fusion Nipah Virus Fusion Glycoprotein Reveals a Novel Hexamer-of-Trimers Assembly
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Kai Xu ,
Contributed equally to this work with: Kai Xu, Yee-Peng Chan, Birgit Bradel-Tretheway, Zeynep Akyol-Ataman, Yongqun Zhu
Affiliation Structural Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America
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Yee-Peng Chan ,
Contributed equally to this work with: Kai Xu, Yee-Peng Chan, Birgit Bradel-Tretheway, Zeynep Akyol-Ataman, Yongqun Zhu
Affiliation Department of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland, United States of America
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Birgit Bradel-Tretheway ,
Contributed equally to this work with: Kai Xu, Yee-Peng Chan, Birgit Bradel-Tretheway, Zeynep Akyol-Ataman, Yongqun Zhu
Affiliation Paul G. Allen School for Global Animal Health, Washington State University, Pullman, Washington, United States of America
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Zeynep Akyol-Ataman ,
Contributed equally to this work with: Kai Xu, Yee-Peng Chan, Birgit Bradel-Tretheway, Zeynep Akyol-Ataman, Yongqun Zhu
Affiliation Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, California, United States of America
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Yongqun Zhu ,
Contributed equally to this work with: Kai Xu, Yee-Peng Chan, Birgit Bradel-Tretheway, Zeynep Akyol-Ataman, Yongqun Zhu
Affiliation Life Sciences Institute and Innovation Center for Cell Biology, Zhejiang University, Hangzhou, Zhejiang, China
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Somnath Dutta,
Affiliation Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, United States of America
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Lianying Yan,
Affiliation Department of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland, United States of America
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YanRu Feng,
Affiliation Department of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland, United States of America
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Lin-Fa Wang,
Affiliations CSIRO Animal, Food and Health Sciences, Australian Animal Health Laboratory, Geelong, Victoria, Australia, Program in Emerging Infectious Diseases, Duke-NUS Graduate Medical School, Singapore, Singapore
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Georgios Skiniotis,
Affiliations Life Sciences Institute, University of Michigan, Ann Arbor, Michigan, United States of America, Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan, United States of America
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Benhur Lee,
Affiliation Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America
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Z. Hong Zhou,
Affiliations Department of Microbiology, Immunology and Molecular Genetics, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, California, United States of America, California NanoSystems Institute, University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, California, United States of America
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Christopher C. Broder ,
* E-mail: nikolovd@mskcc.org (D.B.N.); christopher.broder@usuhs.edu (C.B.); haguilar@vetmed.wsu.edu (H.C.A.)
Affiliation Department of Microbiology and Immunology, Uniformed Services University, Bethesda, Maryland, United States of America
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Hector C. Aguilar ,
* E-mail: nikolovd@mskcc.org (D.B.N.); christopher.broder@usuhs.edu (C.B.); haguilar@vetmed.wsu.edu (H.C.A.)
Affiliation Paul G. Allen School for Global Animal Health, Washington State University, Pullman, Washington, United States of America
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Dimitar B. Nikolov
* E-mail: nikolovd@mskcc.org (D.B.N.); christopher.broder@usuhs.edu (C.B.); haguilar@vetmed.wsu.edu (H.C.A.)
Affiliation Structural Biology Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America
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Crystal Structure of the Pre-fusion Nipah Virus Fusion Glycoprotein Reveals a Novel Hexamer-of-Trimers Assembly
- Kai Xu,
- Yee-Peng Chan,
- Birgit Bradel-Tretheway,
- Zeynep Akyol-Ataman,
- Yongqun Zhu,
- Somnath Dutta,
- Lianying Yan,
- YanRu Feng,
- Lin-Fa Wang,
- Georgios Skiniotis
- Published: December 8, 2015
- https://doi.org/10.1371/journal.ppat.1005322