Human Metapneumovirus Is Capable of Entering Cells by Fusion with Endosomal Membranes

Reagan G. Cox; Bernardo A. Mainou; Monika Johnson; Andrew K. Hastings; Jennifer E. Schuster; Terence S. Dermody; John V. Williams

doi:10.1371/journal.ppat.1005303

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Open Access

Peer-reviewed

Research Article

Human Metapneumovirus Is Capable of Entering Cells by Fusion with Endosomal Membranes

Reagan G. Cox,

Affiliation Department of Pathology, Microbiology, & Immunology, Division of Infectious Diseases, Vanderbilt University School of Medicine; Nashville, Tennessee, United States of America
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Bernardo A. Mainou,

Affiliation Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia, United States of America
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Monika Johnson,

Affiliation Department of Pediatrics, University of Pittsburgh School of Medicine, Children’s Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America
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Andrew K. Hastings,

Affiliation Department of Pathology, Microbiology, & Immunology, Division of Infectious Diseases, Vanderbilt University School of Medicine; Nashville, Tennessee, United States of America
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Jennifer E. Schuster,

Affiliation Department of Pediatrics, Children’s Mercy Hospital, Kansas City, Missouri, United States of America
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Terence S. Dermody,

Affiliations Department of Pathology, Microbiology, & Immunology, Division of Infectious Diseases, Vanderbilt University School of Medicine; Nashville, Tennessee, United States of America, Department of Pediatrics, Division of Infectious Diseases, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
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John V. Williams

* E-mail: jvw@chp.edu

Affiliation Department of Pediatrics, University of Pittsburgh School of Medicine, Children’s Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, United States of America
⨯

Human Metapneumovirus Is Capable of Entering Cells by Fusion with Endosomal Membranes

Reagan G. Cox,
Bernardo A. Mainou,
Monika Johnson,
Andrew K. Hastings,
Jennifer E. Schuster,
Terence S. Dermody,
John V. Williams

Published: December 2, 2015
https://doi.org/10.1371/journal.ppat.1005303

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Membrane fusion
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Cell fusion
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Small interfering RNA
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Endosomes
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Cell membranes
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Integrins
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Viral entry
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Endocytosis
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