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Open Access
Peer-reviewed
Research Article
Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection
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Rami Sommerstein ,
Contributed equally to this work with: Rami Sommerstein, Lukas Flatz, Melissa M. Remy
Current Address: Department of Infectious Diseases, University Hospital, Bern, Switzerland
Affiliations Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland, World Health Organization Collaborating Centre for Vaccine Immunology, University of Geneva, Geneva, Switzerland
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Lukas Flatz ,
Contributed equally to this work with: Rami Sommerstein, Lukas Flatz, Melissa M. Remy
Current Address: Institute of Immunobiology and Clinic for Dermatology and Allergology, Kantonsspital St.Gallen, St. Gallen, Switzerland
Affiliation Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland
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Melissa M. Remy ,
Contributed equally to this work with: Rami Sommerstein, Lukas Flatz, Melissa M. Remy
Affiliations Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland, Division of Experimental Virology, Department of Biomedicine, University of Basel, Basel, Switzerland
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Pauline Malinge,
Affiliation Novimmune SA, Plan-Les-Ouates, Switzerland
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Giovanni Magistrelli,
Affiliation Novimmune SA, Plan-Les-Ouates, Switzerland
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Nicolas Fischer,
Affiliation Novimmune SA, Plan-Les-Ouates, Switzerland
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Mehmet Sahin,
Affiliation Division of Experimental Virology, Department of Biomedicine, University of Basel, Basel, Switzerland
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Andreas Bergthaler,
Current Address: CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria
Affiliation Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland
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Sebastien Igonet,
Current Address: Calixar SAS, Lyon, France
Affiliation Institut Pasteur, Département de Virologie, Unité de Virologie Structurale and CNRS UMR 3569 Virologie, Paris, France
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Jan ter Meulen,
Current Address: Immune Design, Seattle, Washington, United States of America
Affiliation Institute of Virology, Philipps University Marburg, Marburg, Germany
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Dorothée Rigo,
Affiliation Department of Cell Physiology and Metabolism, University of Geneva, Geneva, Switzerland
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Paolo Meda,
Affiliation Department of Cell Physiology and Metabolism, University of Geneva, Geneva, Switzerland
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Nadia Rabah,
Affiliation AFMB, UMR7257 CNRS/Aix Marseille Université, Marseille, France
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Bruno Coutard,
Affiliation AFMB, UMR7257 CNRS/Aix Marseille Université, Marseille, France
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Thomas A. Bowden,
Affiliation Division of Structural Biology, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom
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Paul-Henri Lambert,
Affiliations Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland, World Health Organization Collaborating Centre for Vaccine Immunology, University of Geneva, Geneva, Switzerland
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Claire-Anne Siegrist,
Affiliations Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland, World Health Organization Collaborating Centre for Vaccine Immunology, University of Geneva, Geneva, Switzerland
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Daniel D. Pinschewer
* E-mail: Daniel.Pinschewer@unibas.ch
Affiliations Department of Pathology and Immunology, University of Geneva, Geneva, Switzerland, World Health Organization Collaborating Centre for Vaccine Immunology, University of Geneva, Geneva, Switzerland, Division of Experimental Virology, Department of Biomedicine, University of Basel, Basel, Switzerland
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Arenavirus Glycan Shield Promotes Neutralizing Antibody Evasion and Protracted Infection
- Rami Sommerstein,
- Lukas Flatz,
- Melissa M. Remy,
- Pauline Malinge,
- Giovanni Magistrelli,
- Nicolas Fischer,
- Mehmet Sahin,
- Andreas Bergthaler,
- Sebastien Igonet,
- Jan ter Meulen
- Published: November 20, 2015
- https://doi.org/10.1371/journal.ppat.1005276