Functional Characterization of a Novel Class of Morantel-Sensitive Acetylcholine Receptors in Nematodes

Elise Courtot; Claude L. Charvet; Robin N. Beech; Abdallah Harmache; Adrian J. Wolstenholme; Lindy Holden-Dye; Vincent O’Connor; Nicolas Peineau; Debra J. Woods; Cedric Neveu

doi:10.1371/journal.ppat.1005267

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Open Access

Peer-reviewed

Research Article

Functional Characterization of a Novel Class of Morantel-Sensitive Acetylcholine Receptors in Nematodes

Elise Courtot,

Affiliations INRA, UMR1282 Infectiologie et Santé Publique, Nouzilly, France, Université de François Rabelais de Tours, UMR1282 Infectiologie et Santé Publique, Tours, France
⨯
Claude L. Charvet,

Affiliations INRA, UMR1282 Infectiologie et Santé Publique, Nouzilly, France, Université de François Rabelais de Tours, UMR1282 Infectiologie et Santé Publique, Tours, France
⨯
Robin N. Beech,

Affiliations INRA, UMR1282 Infectiologie et Santé Publique, Nouzilly, France, Institute of Parasitology, McGill University, Macdonald Campus, Sainte Anne de Bellevue, Québec, Canada
⨯
Abdallah Harmache,

Affiliations INRA, UMR1282 Infectiologie et Santé Publique, Nouzilly, France, Université de François Rabelais de Tours, UMR1282 Infectiologie et Santé Publique, Tours, France
⨯
Adrian J. Wolstenholme,

Affiliation Department of Infectious Disease and Center for Tropical and Emerging Global Disease, University of Georgia, Athens, Georgia, United States of America
⨯
Lindy Holden-Dye,

Affiliation School of Biological Sciences, University of Southampton, Southampton, United Kingdom
⨯
Vincent O’Connor,

Affiliation School of Biological Sciences, University of Southampton, Southampton, United Kingdom
⨯
Nicolas Peineau,

Affiliation Université François Rabelais de Tours, Département de physiologie animale, Tours, France
⨯
Debra J. Woods,

Affiliation Veterinary Medicine Research and Development, Zoetis LLC, Kalamazoo, Michigan, United States of America
⨯
Cedric Neveu

* E-mail: cedric.neveu@tours.inra.fr

Affiliations INRA, UMR1282 Infectiologie et Santé Publique, Nouzilly, France, Université de François Rabelais de Tours, UMR1282 Infectiologie et Santé Publique, Tours, France
⨯

Functional Characterization of a Novel Class of Morantel-Sensitive Acetylcholine Receptors in Nematodes

Elise Courtot,
Claude L. Charvet,
Robin N. Beech,
Abdallah Harmache,
Adrian J. Wolstenholme,
Lindy Holden-Dye,
Vincent O’Connor,
Nicolas Peineau,
Debra J. Woods,
Cedric Neveu

Published: December 1, 2015
https://doi.org/10.1371/journal.ppat.1005267

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Caenorhabditis elegans
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Xenopus oocytes
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Nematoda
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Larvae
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Acetylcholine
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