Systematic Identification of Cyclic-di-GMP Binding Proteins in Vibrio cholerae Reveals a Novel Class of Cyclic-di-GMP-Binding ATPases Associated with Type II Secretion Systems

Kevin G. Roelofs; Christopher J. Jones; Sarah R. Helman; Xiaoran Shang; Mona W. Orr; Jonathan R. Goodson; Michael Y. Galperin; Fitnat H. Yildiz; Vincent T. Lee

doi:10.1371/journal.ppat.1005232

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Research Article

Systematic Identification of Cyclic-di-GMP Binding Proteins in Vibrio cholerae Reveals a Novel Class of Cyclic-di-GMP-Binding ATPases Associated with Type II Secretion Systems

Kevin G. Roelofs ,

Contributed equally to this work with: Kevin G. Roelofs, Christopher J. Jones, Sarah R. Helman

Affiliation Department of Cell Biology and Molecular Genetics, University of Maryland at College Park, Maryland, United States of America
⨯
Christopher J. Jones ,

Contributed equally to this work with: Kevin G. Roelofs, Christopher J. Jones, Sarah R. Helman

Affiliation Department of Microbiology and Environmental Toxicology, University of California, Santa Cruz, Santa Cruz, California, United States of America
⨯
Sarah R. Helman ,

Contributed equally to this work with: Kevin G. Roelofs, Christopher J. Jones, Sarah R. Helman

Affiliation Department of Cell Biology and Molecular Genetics, University of Maryland at College Park, Maryland, United States of America
⨯
Xiaoran Shang,

Affiliation Department of Cell Biology and Molecular Genetics, University of Maryland at College Park, Maryland, United States of America
⨯
Mona W. Orr,

Affiliation Department of Cell Biology and Molecular Genetics, University of Maryland at College Park, Maryland, United States of America
⨯
Jonathan R. Goodson,

Affiliation Department of Cell Biology and Molecular Genetics, University of Maryland at College Park, Maryland, United States of America
⨯
Michael Y. Galperin,

Affiliation National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland, United States of America
⨯
Fitnat H. Yildiz,

Affiliation Department of Microbiology and Environmental Toxicology, University of California, Santa Cruz, Santa Cruz, California, United States of America
⨯
Vincent T. Lee

* E-mail: vtlee@umd.edu

Affiliation Department of Cell Biology and Molecular Genetics, University of Maryland at College Park, Maryland, United States of America
⨯

Systematic Identification of Cyclic-di-GMP Binding Proteins in Vibrio cholerae Reveals a Novel Class of Cyclic-di-GMP-Binding ATPases Associated with Type II Secretion Systems

Kevin G. Roelofs,
Christopher J. Jones,
Sarah R. Helman,
Xiaoran Shang,
Mona W. Orr,
Jonathan R. Goodson,
Michael Y. Galperin,
Fitnat H. Yildiz,
Vincent T. Lee

Published: October 27, 2015
https://doi.org/10.1371/journal.ppat.1005232

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Adenosine triphosphatase
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Protein domains
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