Conserved Motifs within Hepatitis C Virus Envelope (E2) RNA and Protein Independently Inhibit T Cell Activation

Open Access

Peer-reviewed

Research Article

Nirjal Bhattarai,

Affiliations Research Service and, The Iowa City Veterans Affairs Medical Center, Iowa City, Iowa, United States of America, The Departments of Internal Medicine and Microbiology, University of Iowa, Iowa City, Iowa, United States of America
⨯
James H. McLinden,

Affiliations Research Service and, The Iowa City Veterans Affairs Medical Center, Iowa City, Iowa, United States of America, The Departments of Internal Medicine and Microbiology, University of Iowa, Iowa City, Iowa, United States of America
⨯
Jinhua Xiang,

Affiliations Research Service and, The Iowa City Veterans Affairs Medical Center, Iowa City, Iowa, United States of America, The Departments of Internal Medicine and Microbiology, University of Iowa, Iowa City, Iowa, United States of America
⨯
Thomas M. Kaufman,

Affiliations Research Service and, The Iowa City Veterans Affairs Medical Center, Iowa City, Iowa, United States of America, The Departments of Internal Medicine and Microbiology, University of Iowa, Iowa City, Iowa, United States of America
⨯
Jack T. Stapleton

* E-mail: jack-stapleton@uiowa.edu

Affiliations Research Service and, The Iowa City Veterans Affairs Medical Center, Iowa City, Iowa, United States of America, The Departments of Internal Medicine and Microbiology, University of Iowa, Iowa City, Iowa, United States of America
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T cell receptors
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TCR signaling cascade
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Signal inhibition
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T cells
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Hepatitis C virus
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Phosphorylation
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Protein expression
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Immune receptor signaling
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