Simian Immunodeficiency Virus Infection of Chimpanzees (Pan troglodytes) Shares Features of Both Pathogenic and Non-pathogenic Lentiviral Infections

Edward J. D. Greenwood; Fabian Schmidt; Ivanela Kondova; Henk Niphuis; Vida L. Hodara; Leah Clissold; Kirsten McLay; Bernadette Guerra; Sharon Redrobe; Luis D. Giavedoni; Robert E. Lanford; Krishna K. Murthy; François Rouet; Jonathan L. Heeney

doi:10.1371/journal.ppat.1005146

Loading metrics

Open Access

Peer-reviewed

Research Article

Simian Immunodeficiency Virus Infection of Chimpanzees (Pan troglodytes) Shares Features of Both Pathogenic and Non-pathogenic Lentiviral Infections

Edward J. D. Greenwood,

Current address: Cambridge Institute for Medical Research, University of Cambridge, Cambridge, United Kingdom

Affiliation Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom
⨯
Fabian Schmidt,

Current address: Aaron Diamond AIDS Research Center, The Rockefeller University, New York, New York, United States of America

Affiliation Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom
⨯
Ivanela Kondova,

Affiliation Division of Pathology and Microbiology, Biomedical Primate Research Centre, Rijswijk, The Netherlands
⨯
Henk Niphuis,

Affiliation Department of Virology, Biomedical Primate Research Centre, Rijswijk, The Netherlands
⨯
Vida L. Hodara,

Affiliations Department of Virology and Immunology, Texas Biomedical Research Institute, San Antonio, Texas, United States of America, Southwest National Primate Research Center, San Antonio, Texas, United States of America
⨯
Leah Clissold,

Affiliation The Genome Analysis Centre (TGAC), Norwich, United Kingdom
⨯
Kirsten McLay,

Affiliation The Genome Analysis Centre (TGAC), Norwich, United Kingdom
⨯
Bernadette Guerra,

Affiliation Department of Virology and Immunology, Texas Biomedical Research Institute, San Antonio, Texas, United States of America
⨯
Sharon Redrobe,

Affiliation Twycross Zoo - East Midland Zoological Society, Atherstone, United Kingdom
⨯
Luis D. Giavedoni,

Affiliations Department of Virology and Immunology, Texas Biomedical Research Institute, San Antonio, Texas, United States of America, Southwest National Primate Research Center, San Antonio, Texas, United States of America
⨯
Robert E. Lanford,

Affiliations Department of Virology and Immunology, Texas Biomedical Research Institute, San Antonio, Texas, United States of America, Southwest National Primate Research Center, San Antonio, Texas, United States of America
⨯
Krishna K. Murthy,

Current address: IDS Consulting, San Antonio, Texas, United States of America

Affiliation Department of Virology and Immunology, Texas Biomedical Research Institute, San Antonio, Texas, United States of America
⨯
François Rouet,

Current address: Unité VIH/Hépatites, Institut Pasteur du Cambodge, Phnom-Penh, Cambodia

Affiliation Laboratoire de Rétrovirologie, Centre International de Recherches Médicales de Franceville, Franceville, Gabon
⨯
Jonathan L. Heeney

* E-mail: jlh66@cam.ac.uk

Affiliation Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom
⨯

Simian Immunodeficiency Virus Infection of Chimpanzees (Pan troglodytes) Shares Features of Both Pathogenic and Non-pathogenic Lentiviral Infections

Edward J. D. Greenwood,
Fabian Schmidt,
Ivanela Kondova,
Henk Niphuis,
Vida L. Hodara,
Leah Clissold,
Kirsten McLay,
Bernadette Guerra,
Sharon Redrobe,
Luis D. Giavedoni

Published: September 11, 2015
https://doi.org/10.1371/journal.ppat.1005146

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Chimpanzees
Is the Subject Area "Chimpanzees" applicable to this article?

Thanks for your feedback.
T cells
Is the Subject Area "T cells" applicable to this article?

Thanks for your feedback.
HIV-1
Is the Subject Area "HIV-1" applicable to this article?

Thanks for your feedback.
SIV
Is the Subject Area "SIV" applicable to this article?

Thanks for your feedback.
Viral load
Is the Subject Area "Viral load" applicable to this article?

Thanks for your feedback.
Primates
Is the Subject Area "Primates" applicable to this article?

Thanks for your feedback.
Immune activation
Is the Subject Area "Immune activation" applicable to this article?

Thanks for your feedback.
Blood plasma
Is the Subject Area "Blood plasma" applicable to this article?

Thanks for your feedback.