Virulence of Group A Streptococci Is Enhanced by Human Complement Inhibitors

David Ermert; Jutamas Shaughnessy; Thorsten Joeris; Jakub Kaplan; Catherine J. Pang; Evelyn A. Kurt-Jones; Peter A. Rice; Sanjay Ram; Anna M. Blom

doi:10.1371/journal.ppat.1005043

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Open Access

Peer-reviewed

Research Article

Virulence of Group A Streptococci Is Enhanced by Human Complement Inhibitors

David Ermert,

Affiliations Division of Medical Protein Chemistry, Department of Translational Medicine, Lund University, Malmö, Sweden, Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Jutamas Shaughnessy,

Affiliation Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Thorsten Joeris,

Affiliations Section of Immunology and Vaccinology, National Veterinary Institute, Technical University of Denmark, Frederiksberg C, Denmark, Department of Experimental Medical Science, Immunology section, Lund University, Lund, Sweden
⨯
Jakub Kaplan,

Affiliation Division of Medical Protein Chemistry, Department of Translational Medicine, Lund University, Malmö, Sweden
⨯
Catherine J. Pang,

Affiliation Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Evelyn A. Kurt-Jones,

Affiliation Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Peter A. Rice,

Affiliation Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Sanjay Ram,

Affiliation Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America
⨯
Anna M. Blom

* E-mail: anna.blom@med.lu.se

Affiliation Division of Medical Protein Chemistry, Department of Translational Medicine, Lund University, Malmö, Sweden
⨯

Virulence of Group A Streptococci Is Enhanced by Human Complement Inhibitors

David Ermert,
Jutamas Shaughnessy,
Thorsten Joeris,
Jakub Kaplan,
Catherine J. Pang,
Evelyn A. Kurt-Jones,
Peter A. Rice,
Sanjay Ram,
Anna M. Blom

Published: July 22, 2015
https://doi.org/10.1371/journal.ppat.1005043

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