α2-Macroglobulin Can Crosslink Multiple Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) Molecules and May Facilitate Adhesion of Parasitized Erythrocytes

Liz Stevenson; Erik Laursen; Graeme J. Cowan; Betty Bandoh; Lea Barfod; David R. Cavanagh; Gregers R. Andersen; Lars Hviid

doi:10.1371/journal.ppat.1005022

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Peer-reviewed

Research Article

α₂-Macroglobulin Can Crosslink Multiple Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) Molecules and May Facilitate Adhesion of Parasitized Erythrocytes

Liz Stevenson,

Affiliation Centre for Medical Parasitology, Department of Immunology and Microbiology (ISIM), Faculty of Health and Medical Sciences, University of Copenhagen and Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark
⨯
Erik Laursen,

Affiliation Centre for Medical Parasitology, Department of Immunology and Microbiology (ISIM), Faculty of Health and Medical Sciences, University of Copenhagen and Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark
⨯
Graeme J. Cowan,

Affiliation Institute of Immunology and Infection Research, Center for Immunity, Infection and Evolution, University of Edinburgh, Edinburgh, United Kingdom
⨯
Betty Bandoh,

Affiliations Centre for Medical Parasitology, Department of Immunology and Microbiology (ISIM), Faculty of Health and Medical Sciences, University of Copenhagen and Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark, Noguchi Memorial Institute for Medical Research, University of Ghana, Legon, Ghana
⨯
Lea Barfod,

Affiliation Centre for Medical Parasitology, Department of Immunology and Microbiology (ISIM), Faculty of Health and Medical Sciences, University of Copenhagen and Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark
⨯
David R. Cavanagh,

Affiliation Institute of Immunology and Infection Research, Center for Immunity, Infection and Evolution, University of Edinburgh, Edinburgh, United Kingdom
⨯
Gregers R. Andersen,

Affiliation Department of Molecular Biology and Genetics, University of Aarhus, Aarhus, Denmark
⨯
Lars Hviid

* E-mail: lhviid@sund.ku.dk

Affiliation Centre for Medical Parasitology, Department of Immunology and Microbiology (ISIM), Faculty of Health and Medical Sciences, University of Copenhagen and Department of Infectious Diseases, Copenhagen University Hospital (Rigshospitalet), Copenhagen, Denmark
⨯

α₂-Macroglobulin Can Crosslink Multiple Plasmodium falciparum Erythrocyte Membrane Protein 1 (PfEMP1) Molecules and May Facilitate Adhesion of Parasitized Erythrocytes

Liz Stevenson,
Erik Laursen,
Graeme J. Cowan,
Betty Bandoh,
Lea Barfod,
David R. Cavanagh,
Gregers R. Andersen,
Lars Hviid

Published: July 2, 2015
https://doi.org/10.1371/journal.ppat.1005022

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