Phenylbutyrate Is Bacteriostatic against Mycobacterium tuberculosis and Regulates the Macrophage Response to Infection, Synergistically with 25-Hydroxy-Vitamin D₃

Open Access

Peer-reviewed

Research Article

Anna K. Coussens,

Affiliations Clinical Infectious Diseases Research Initiative, Institute of Infectious Disease & Molecular Medicine, University of Cape Town, South Africa, Division of Mycobacterial Research, MRC National Institute of Medical Research, London, United Kingdom
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Robert J. Wilkinson ,

* E-mail: r.j.wilkinson@imperial.ac.uk

Affiliations Clinical Infectious Diseases Research Initiative, Institute of Infectious Disease & Molecular Medicine, University of Cape Town, South Africa, Department of Medicine, Imperial College London, London, United Kingdom, The Francis Crick Institute, Mill Hill Laboratory, London, United Kingdom
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Adrian R. Martineau

Affiliations Division of Mycobacterial Research, MRC National Institute of Medical Research, London, United Kingdom, Blizard Institute, Barts and The London School of Medicine, Queen Mary University of London, London, United Kingdom
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Mycobacterium tuberculosis
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Gene expression
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Macrophages
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Gene regulation
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Vitamin D
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MAPK signaling cascades
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Secretion
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Vitamins
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