Geometric Constraints Dominate the Antigenic Evolution of Influenza H3N2 Hemagglutinin

Open Access

Peer-reviewed

Research Article

Austin G. Meyer,

Affiliations Department of Integrative Biology, Institute for Cellular and Molecular Biology and Center for Computational Biology and Bioinformatics, The University of Texas at Austin, Austin, Texas, United States of America, School of Medicine, Texas Tech University Health Sciences Center, Lubbock, Texas, United States of America
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Claus O. Wilke

* E-mail: wilke@austin.utexas.edu

Affiliation Department of Integrative Biology, Institute for Cellular and Molecular Biology and Center for Computational Biology and Bioinformatics, The University of Texas at Austin, Austin, Texas, United States of America
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Evolutionary rate
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Evolutionary immunology
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Viral evolution
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Antibodies
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Influenza
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Protein structure
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Molecular evolution
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Immune system
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