IRF-5-Mediated Inflammation Limits CD8+ T Cell Expansion by Inducing HIF-1α and Impairing Dendritic Cell Functions during Leishmania Infection

Open Access

Peer-reviewed

Research Article

IRF-5-Mediated Inflammation Limits CD8⁺ T Cell Expansion by Inducing HIF-1α and Impairing Dendritic Cell Functions during Leishmania Infection

Akil Hammami,

Affiliation INRS—Institut Armand-Frappier, Laval, Quebec, Canada
⨯
Tania Charpentier,

Affiliation INRS—Institut Armand-Frappier, Laval, Quebec, Canada
⨯
Mélina Smans,

Affiliation INRS—Institut Armand-Frappier, Laval, Quebec, Canada
⨯
Simona Stäger

* E-mail: simona.stager@iaf.inrs.ca

Affiliation INRS—Institut Armand-Frappier, Laval, Quebec, Canada
⨯

T cells
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Cytotoxic T cells
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Leishmania donovani
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Parasitic diseases
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Inflammation
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Amastigotes
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Spleen
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Cytokines
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