The Myelin and Lymphocyte Protein MAL Is Required for Binding and Activity of Clostridium perfringens ε-Toxin

Kareem Rashid Rumah; Yinghua Ma; Jennifer R. Linden; Myat Lin Oo; Josef Anrather; Nicole Schaeren-Wiemers; Miguel A. Alonso; Vincent A. Fischetti; Mark S. McClain; Timothy Vartanian

doi:10.1371/journal.ppat.1004896

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Open Access

Peer-reviewed

Research Article

The Myelin and Lymphocyte Protein MAL Is Required for Binding and Activity of Clostridium perfringens ε-Toxin

Kareem Rashid Rumah ,

Contributed equally to this work with: Kareem Rashid Rumah, Yinghua Ma, Jennifer R. Linden

Affiliations Brain and Mind Research Institute, Weill Cornell Medical College, New York City, New York, United States of America, Laboratory of Bacterial Pathogenesis and Immunology, The Rockefeller University, New York City, New York, United States of America
⨯
Yinghua Ma ,

Contributed equally to this work with: Kareem Rashid Rumah, Yinghua Ma, Jennifer R. Linden

Affiliation Brain and Mind Research Institute, Weill Cornell Medical College, New York City, New York, United States of America
⨯
Jennifer R. Linden ,

Contributed equally to this work with: Kareem Rashid Rumah, Yinghua Ma, Jennifer R. Linden

Affiliation Brain and Mind Research Institute, Weill Cornell Medical College, New York City, New York, United States of America
⨯
Myat Lin Oo,

Affiliation Brain and Mind Research Institute, Weill Cornell Medical College, New York City, New York, United States of America
⨯
Josef Anrather,

Affiliation Brain and Mind Research Institute, Weill Cornell Medical College, New York City, New York, United States of America
⨯
Nicole Schaeren-Wiemers,

Affiliation Neurobiology, Department of Biomedicine, University Hospital Basel, University of Basel, Basel, Switzerland
⨯
Miguel A. Alonso,

Affiliation Centro de Biología Molecular Severo Ochoa, CSIC-UAM, Cantoblanco, Madrid, Spain
⨯
Vincent A. Fischetti,

Affiliation Laboratory of Bacterial Pathogenesis and Immunology, The Rockefeller University, New York City, New York, United States of America
⨯
Mark S. McClain,

Affiliation Department of Medicine, Division of Infectious Diseases, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America
⨯
Timothy Vartanian

* E-mail: tiv2002@med.cornell.edu

Affiliation Brain and Mind Research Institute, Weill Cornell Medical College, New York City, New York, United States of America
⨯

The Myelin and Lymphocyte Protein MAL Is Required for Binding and Activity of Clostridium perfringens ε-Toxin

Kareem Rashid Rumah,
Yinghua Ma,
Jennifer R. Linden,
Myat Lin Oo,
Josef Anrather,
Nicole Schaeren-Wiemers,
Miguel A. Alonso,
Vincent A. Fischetti,
Mark S. McClain,
Timothy Vartanian

Published: May 20, 2015
https://doi.org/10.1371/journal.ppat.1004896

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